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A pilot study of a wearable apnoea detection device

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Title: A pilot study of a wearable apnoea detection device
Author(s): Rodriguez-Villegas, E
Chen, G
Radcliffe, J
Duncan, J
Item Type: Journal Article
Abstract: Rationale Current techniques for monitoring patients for apnoea suffer from significant limitations. These include insufficient availability to meet diagnostic needs, cost, accuracy of results in the presence of artefacts and difficulty of use in unsupervised conditions. Objectives We created and clinically tested a novel miniature medical device that targets overcoming these limitations. Methods We studied 20 healthy control participants and 10 patients who had been referred for sleep apnoea diagnosis. The performances of the new system and also of the Food and Drug Administration (FDA) approved SOMNO clinical system, conventionally used for sleep apnoea diagnosis were evaluated under the same conditions. Both systems were tested during a normal night of sleep in controls and patients. Their performances were quantified in terms of detection of apnoea and hypopnoea in individual 10 s epochs, which were compared with scoring of signals by a blinded clinician. Main results For spontaneous apnoeas during natural sleep and considering the clinician scorer as the gold standard, the new wearable apnoea detection device had 88.6% sensitivity and 99.6% specificity. In comparison the SOMNO system had 14.3% sensitivity and 99.3% specificity. The novel device had been specifically designed to detect apnoea, but if apnoea and hypopnoea during sleep were both considered in the assessment, the sensitivity and specificity were 77.1% and 99.7%, respectively, versus 54% and 98.5%, respectively, for the SOMNO. Conclusions The performance of the novel device compares very well to the scoring by an experienced clinician even in the presence of breathing artefacts, in this small pilot study. This can potentially make it a real solution for apnoea home monitoring.
Publication Date: 3-Oct-2014
Date of Acceptance: 27-Aug-2014
URI: http://hdl.handle.net/10044/1/40620
DOI: http://dx.doi.org/10.1136/bmjopen-2014-005299
ISSN: 2044-6055
Publisher: BMJ Publishing Group
Journal / Book Title: BMJ Open
Volume: 4
Issue: 10
Copyright Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Keywords: Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
OBSTRUCTIVE SLEEP-APNEA
INTENSIVE-CARE-UNIT
SUDDEN UNEXPECTED DEATH
DIAGNOSIS
DISEASE
MECHANISMS
ANESTHESIA
HYPOPNEA
EPILEPSY
IMPACT
RESPIRATORY MEDICINE (see Thoracic Medicine)
SLEEP MEDICINE
Adult
Aged
Aged, 80 and over
Case-Control Studies
Equipment Design
Female
Humans
Male
Middle Aged
Monitoring, Ambulatory
Pilot Projects
Polysomnography
Sensitivity and Specificity
Sleep Apnea, Central
Sleep Apnea, Obstructive
Young Adult
Humans
Sleep Apnea, Central
Sleep Apnea, Obstructive
Monitoring, Ambulatory
Polysomnography
Sensitivity and Specificity
Case-Control Studies
Pilot Projects
Equipment Design
Adult
Aged
Aged, 80 and over
Middle Aged
Female
Male
Young Adult
Publication Status: Published
Article Number: e005299
Appears in Collections:Faculty of Engineering
Electrical and Electronic Engineering



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