Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope

Title: Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope
Authors: Clancy, NT
Arya, S
Stoyanov, D
Singh, M
Hanna, GB
Elson, DS
Item Type: Journal Article
Abstract: Intraoperative monitoring of tissue oxygen saturation (StO2) has potentially important applications in procedures such as organ transplantation or colorectal surgery, where successful reperfusion affects the viability and integrity of repaired tissues. In this paper a liquid crystal tuneable filter-based multispectral imaging (MSI) laparoscope is described. Motion-induced image misalignments are reduced, using feature-based registration, before regression of the tissue reflectance spectra to calculate relative quantities of oxy- and deoxyhaemoglobin. The laparoscope was validated in vivo, during porcine abdominal surgery, by making parallel MSI and blood gas measurements of the small bowel vasculature. Ischaemic conditions were induced by local occlusion of the mesenteric arcade and monitored using the system. The MSI laparoscope was capable of measuring StO2 over a wide range (30-100%) with a temporal error of ± 7.5%. The imager showed sensitivity to spatial changes in StO2 during dynamic local occlusions, as well as tracking the recovery of tissues post-occlusion.
Issue Date: 30-Sep-2015
Date of Acceptance: 27-Sep-2015
URI: http://hdl.handle.net/10044/1/39546
DOI: https://dx.doi.org/10.1364/BOE.6.004179
ISSN: 2156-7085
Publisher: Optical Society of America: Open Access Journals
Start Page: 4179
End Page: 4190
Journal / Book Title: Biomedical Optics Express
Volume: 6
Issue: 10
Copyright Statement: © 2015 Optical Society of America
Sponsor/Funder: Commission of the European Communities
Department of Health
Funder's Grant Number: 242991
HTD 240
Keywords: Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemical Research Methods
Optics
Radiology, Nuclear Medicine & Medical Imaging
Biochemistry & Molecular Biology
BIOLOGICAL TISSUES
NITRIC-OXIDE
SYSTEM
PERFUSION
SURGERY
HEART
(110.4234) Multispectral and hyperspectral imaging
(170.0170) Medical optics and biotechnology
(170.1610) Clinical applications
(170.2150) Endoscopic imaging
(170.2655) Functional monitoring and imaging
(170.6510) Spectroscopy, tissue diagnostics
Publication Status: Published
Open Access location: https://dx.doi.org/10.1364/BOE.6.004179
Appears in Collections:Division of Surgery



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