Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance

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Title: Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance
Authors: Nestal de Moraes, G
Bella, L
Zona, S
Burton, MJ
Lam, EW
Item Type: Journal Article
Issue Date: 31-Jan-2016
Date of Acceptance: 8-Nov-2015
URI: http://hdl.handle.net/10044/1/39197
DOI: https://dx.doi.org/10.2174/1389450115666141122211549#sthash.fye57TW9.dpuf
ISSN: 1873-5592
Publisher: Bentham Science Publishers
Start Page: 164
End Page: 177
Journal / Book Title: Current Drug Targets
Volume: 17
Issue: 2
Copyright Statement: The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/126258/article.
Sponsor/Funder: Cancer Research UK
Breast Cancer Now
Breast Cancer Campaign and Breakthrough Breast Cancer
Funder's Grant Number: C37/A12011
2012NovemberPhD016
2012MayPR070
Keywords: Science & Technology
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Cancer
DNA damage
drug resistance
FOXM1
FOXO3a
genotoxic agents
transcriptional targets
FORKHEAD TRANSCRIPTION FACTORS
BREAST-CANCER CELLS
DOUBLE-STRAND BREAKS
HUMAN EPITHELIAL-CELLS
OXIDATIVE-STRESS
PROTEIN-KINASE
FOXM1 EXPRESSION
EPIRUBICIN TREATMENT
GENOMIC INSTABILITY
COLORECTAL-CANCER
1115 Pharmacology And Pharmaceutical Sciences
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine



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