Mitochondria and senescence: new actors for an old play.

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Title: Mitochondria and senescence: new actors for an old play.
Author(s): Herranz, N
Gil, J
Item Type: Journal Article
Abstract: Mitochondrial dysfunction has been linked to both cellular senescence and ageing. Despite the relationship, it is still unclear whether mitochondria have a causal role in senescence. In this issue of The EMBO Journal, Correia‐Melo et al (2016) combine targeted depletion of mitochondria with impairment of their biogenesis to demonstrate that decreased numbers of mitochondria impair the senescence response. Their results suggest that targeting mitochondria could reduce the detrimental effects of senescence during ageing.
Publication Date: 1-Apr-2016
Date of Acceptance: 23-Feb-2016
ISSN: 0261-4189
Publisher: EMBO Press
Start Page: 701
End Page: 702
Journal / Book Title: EMBO Journal
Volume: 35
Issue: 7
Copyright Statement: This is the peer reviewed version of the following article: Herranz, N. and Gil, J. (2016), Mitochondria and senescence: new actors for an old play. EMBO J, 35: 701–702, which has been published in final form at  This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Keywords: Developmental Biology
06 Biological Sciences
08 Information And Computing Sciences
11 Medical And Health Sciences
Publication Status: Published
Appears in Collections:Clinical Sciences
Molecular Sciences
Faculty of Medicine

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