HIV-associated anal cancer

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Title: HIV-associated anal cancer
Authors: Newsom-Davis, T
Bower, M
Item Type: Journal Article
Abstract: HIV-associated anal carcinoma, a non-AIDS-defining cancer, is a human papillomavirus-associated malignancy with a spectrum of preinvasive changes. The standardized incidence ratio for anal cancer in patients with HIV/AIDS is 20-50. Algorithms for anal cancer screening include anal cytology followed by high-resolution anoscopy for those with abnormal findings. Outpatient topical treatments for anal intraepithelial neoplasia include infrared coagulation therapy, trichloroacetic acid, and imiquimod. The development of cost-effective national screening programs for HIV-associated anal cancer remains a challenge.
Issue Date: 8-Dec-2010
Date of Acceptance: 8-Dec-2010
ISSN: 1757-5931
Publisher: Faculty of 1000 Ltd
Journal / Book Title: F1000 Medicine Reports
Volume: 2
Copyright Statement: This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes.
Publication Status: Published
Article Number: 85
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine

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