HIV-associated anal cancer

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Title: HIV-associated anal cancer
Authors: Newsom-Davis, T
Bower, M
Item Type: Journal Article
Abstract: HIV-associated anal carcinoma, a non-AIDS-defining cancer, is a human papillomavirus-associated malignancy with a spectrum of preinvasive changes. The standardized incidence ratio for anal cancer in patients with HIV/AIDS is 20-50. Algorithms for anal cancer screening include anal cytology followed by high-resolution anoscopy for those with abnormal findings. Outpatient topical treatments for anal intraepithelial neoplasia include infrared coagulation therapy, trichloroacetic acid, and imiquimod. The development of cost-effective national screening programs for HIV-associated anal cancer remains a challenge.
Issue Date: 8-Dec-2010
Date of Acceptance: 8-Dec-2010
URI: http://hdl.handle.net/10044/1/38378
DOI: http://dx.doi.org/10.3410/M2-85
ISSN: 1757-5931
Publisher: Faculty of 1000 Ltd
Journal / Book Title: F1000 Medicine Reports
Volume: 2
Copyright Statement: This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes.
Publication Status: Published
Article Number: 85
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine



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