Altmetric

Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

Title: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion
Authors: Nguyen, VTM
Barozzi, I
Faronato, M
Lombardo, Y
Steel, JH
Patel, N
Darbre, P
Castellano, L
Gyorffy, B
Woodley, L
Meira, A
Patten, DL
Vircillo, V
Periyasamy, M
Ali, S
Frige, G
Minucci, S
Coombes, RC
Magnani, L
Item Type: Journal Article
Issue Date: 27-Nov-2015
Date of Acceptance: 27-Nov-2015
URI: http://hdl.handle.net/10044/1/33830
DOI: https://dx.doi.org/10.1038/ncomms10044
ISSN: 2041-1723
Publisher: Nature Publishing Group
Journal / Book Title: Nature Communications
Volume: 6
Copyright Statement: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Sponsor/Funder: Cancer Research UK
Cancer Research UK
National Institute for Health Research
Breast Cancer Campaign and Breakthrough Breast Cancer
Funder's Grant Number: C37/A12011
C1312/A15589
RDEMC 79560
2013MaySP013
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
POSITIVE BREAST-CANCER
ESTROGEN-RECEPTOR-ALPHA
MEVALONATE PATHWAY
GENE-EXPRESSION
SUPER-ENHANCERS
PIONEER FACTORS
IDENTITY GENES
IN-VITRO
CELLS
RESISTANCE
Animals
Antineoplastic Agents, Hormonal
Aromatase Inhibitors
Biosynthetic Pathways
Blotting, Western
Breast Neoplasms
Cholesterol
Chromatin Immunoprecipitation
Drug Resistance, Neoplasm
Epigenesis, Genetic
Estrogen Receptor alpha
Female
Humans
Hydroxycholesterols
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Immunohistochemistry
In Vitro Techniques
MCF-7 Cells
Mice
Mice, SCID
Neoplasm Invasiveness
Neoplasm Transplantation
Real-Time Polymerase Chain Reaction
Up-Regulation
Animals
Humans
Mice
Mice, SCID
Breast Neoplasms
Neoplasm Invasiveness
Cholesterol
Hydroxycholesterols
Estrogen Receptor alpha
Antineoplastic Agents, Hormonal
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Aromatase Inhibitors
Blotting, Western
Immunohistochemistry
Chromatin Immunoprecipitation
Neoplasm Transplantation
Epigenesis, Genetic
Up-Regulation
Drug Resistance, Neoplasm
Female
Biosynthetic Pathways
Real-Time Polymerase Chain Reaction
MCF-7 Cells
In Vitro Techniques
MD Multidisciplinary
Publication Status: Published
Open Access location: http://www.nature.com/ncomms/2015/151127/ncomms10044/full/ncomms10044.html
Article Number: 10044
Appears in Collections:Division of Surgery
Division of Cancer



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Creative Commonsx