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A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway

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Title: A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway
Author(s): Cheraghchi-Bashi, A
Parker, CA
Curry, E
Salazar, J-F
Gungor, H
Saleem, A
Cunnea, P
Rama, N
Salinas, C
Mills, GB
Morris, SR
Kumar, R
Gabra, H
Stronach, EA
Item Type: Journal Article
Publication Date: 19-Oct-2015
Date of Acceptance: 30-Sep-2015
URI: http://hdl.handle.net/10044/1/32473
DOI: http://dx.doi.org/10.18632/oncotarget.6153
ISSN: 1949-2553
Publisher: Impact Journals
Start Page: 41736
End Page: 41749
Journal / Book Title: Oncotarget
Volume: 6
Issue: 39
Copyright Statement: This article is licensed under a Creative Commons Attribution 3.0 License.
Keywords: Science & Technology
Life Sciences & Biomedicine
Oncology
Cell Biology
ovarian cancer
platinum resistance
biomarkers
proteomics
AKT
SEROUS OVARIAN-CANCER
PHASE PROTEIN ARRAY
PLATINUM RESISTANCE
ACTIVATION
YB-1
PHOSPHORYLATION
EVOLUTION
APOPTOSIS
RECEPTOR
AKT
biomarkers
ovarian cancer
platinum resistance
proteomics
Publication Status: Published
Appears in Collections:Division of Surgery
Division of Cancer



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