Psychological treatments for depression in pre-adolescent children (12 years and younger): systematic review and meta-analysis of randomised controlled trials.

Title: Psychological treatments for depression in pre-adolescent children (12 years and younger): systematic review and meta-analysis of randomised controlled trials.
Author(s): Forti-Buratti, MA
Saikia, R
Wilkinson, EL
Ramchandani, PG
Item Type: Journal Article
Abstract: The objective of this study was to evaluate the efficacy of psychological treatments for depression in pre-adolescent children, a disorder affecting 1-2 % of children in this age range. A systematic review of studies of psychological interventions to treat depressive disorder in pre-adolescent children (aged up to 12-years-old) was carried out. The primary outcome was level of depressive symptoms. Studies were found using Medline, PsycINFO, EMBASE and Web of Knowledge databases and selected on several criteria. Only randomised controlled trials were included. Where individual studies covered a broader age range (usually including adolescents up to age 18 years), authors of those studies were contacted and requested to provide individual patient level data for those aged 12 years and younger. 2822 abstracts were reviewed, and from these 124 full text articles were reviewed, yielding 7 studies for which we were able to access appropriate data for this review. 5 of these studies evaluated cognitive behaviour therapy (CBT). Combined results from these studies suggest that there is a lack of evidence that CBT is better than no treatment [standard mean difference -0.342 (95 % confidence interval -0.961, 0.278)], although the number of participants included in the trials was relatively small. The evidence for efficacy of family therapy and psychodynamic therapy is even more limited. The very limited number of participants in randomised controlled trials means that there is inconclusive evidence for the psychological treatment of depression in children aged 12 years and below. Given the prevalence and significant impact of this disorder, there is an urgent need to establish the effectiveness or otherwise of psychological intervention.
Publication Date: 11-Mar-2016
Date of Acceptance: 23-Feb-2016
ISSN: 1435-165X
Publisher: Springer Verlag (Germany)
Start Page: 1045
End Page: 1054
Journal / Book Title: European Child & Adolescent Psychiatry
Volume: 25
Issue: 10
Copyright Statement: © Springer-Verlag Berlin Heidelberg 2016. The final publication is available at Springer via
Keywords: Children
Psychological treatment
Systematic review
Developmental & Child Psychology
1103 Clinical Sciences
1701 Psychology
Publication Status: Published
Appears in Collections:Department of Medicine
Faculty of Medicine

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