Engineered repressors are potent inhibitors of androgen receptor activity

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Title: Engineered repressors are potent inhibitors of androgen receptor activity
Author(s): Brooke, GN
Powell, SM
Lavery, DN
Waxman, J
Buluwela, L
Ali, S
Bevan, CL
Item Type: Journal Article
Publication Date: 21-Jan-2014
Date of Acceptance: 20-Nov-2013
URI: http://hdl.handle.net/10044/1/29638
DOI: https://dx.doi.org/10.18632/oncotarget.1360
ISSN: 1949-2553
Publisher: Impact Journals
Start Page: 959
End Page: 969
Journal / Book Title: Oncotarget
Volume: 5
Issue: 4
Sponsor/Funder: The Prostate Cancer Research Foundation
Imperial College Healthcare Charity
Imperial College Healthcare Charity
Imperial Innovations Ltd
Funder's Grant Number: n/a
N/A
WSCC_P32333
6038
Copyright Statement: © 2014 The Authors. Licensed under a Creative Commons Attribution 3.0 License.
Keywords: Science & Technology
Life Sciences & Biomedicine
Oncology
Cell Biology
CELL BIOLOGY
ONCOLOGY
Androgen receptor
Prostate cancer
Anti-androgen
Castrate resistant prostate cancer
PROSTATE-CANCER
NUCLEAR RECEPTOR
TERMINAL INTERACTION
ESTROGEN-RECEPTOR
BINDING
COREPRESSOR
ACTIVATION
EXPRESSION
DOMAIN
GENE
Androgen Receptor Antagonists
Animals
COS Cells
Cell Line, Tumor
Cercopithecus aethiops
Humans
Male
Molecular Targeted Therapy
Prostatic Neoplasms
Prostatic Neoplasms, Castration-Resistant
Protein Engineering
Receptors, Androgen
Recombinant Fusion Proteins
Repressor Proteins
Signal Transduction
COS Cells
Cell Line, Tumor
Animals
Cercopithecus aethiops
Humans
Prostatic Neoplasms
Receptors, Androgen
Recombinant Fusion Proteins
Repressor Proteins
Protein Engineering
Signal Transduction
Male
Molecular Targeted Therapy
Androgen Receptor Antagonists
Prostatic Neoplasms, Castration-Resistant
Science & Technology
Life Sciences & Biomedicine
Oncology
Cell Biology
CELL BIOLOGY
ONCOLOGY
Androgen receptor
Prostate cancer
Anti-androgen
Castrate resistant prostate cancer
PROSTATE-CANCER
NUCLEAR RECEPTOR
TERMINAL INTERACTION
ESTROGEN-RECEPTOR
BINDING
COREPRESSOR
ACTIVATION
EXPRESSION
DOMAIN
GENE
Publication Status: Published
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine



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