A Central Role for GRB10 in Regulation of Islet Function in Man

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Title: A Central Role for GRB10 in Regulation of Islet Function in Man
Author(s): Prokopenko, I
Poon, W
Maegi, R
Prasad, RB
Salehi, SA
Almgren, P
Osmark, P
Bouatia-Naji, N
Wierup, N
Fall, T
Stancakova, A
Barker, A
Lagou, V
Osmond, C
Xie, W
Lahti, J
Jackson, AU
Cheng, Y-C
Liu, J
O'Connell, JR
Blomstedt, PA
Fadista, J
Alkayyali, S
Dayeh, T
Ahlqvist, E
Taneera, J
Lecoeur, C
Kumar, A
Hansson, O
Hansson, K
Voight, BF
Kang, HM
Levy-Marchal, C
Vatin, V
Palotie, A
Syvanen, A-C
Mari, A
Weedon, MN
Loos, RJF
Ong, KK
Nilsson, P
Isomaa, B
Tuomi, T
Wareham, NJ
Stumvoll, M
Widen, E
Lakka, TA
Langenberg, C
Tonjes, A
Rauramaa, R
Kuusisto, J
Frayling, TM
Froguel, P
Walker, M
Eriksson, JG
Ling, C
Kovacs, P
Ingelsson, E
McCarthy, MI
Shuldiner, AR
Silver, KD
Laakso, M
Groop, L
Lyssenko, V
Item Type: Journal Article
Publication Date: 1-Apr-2014
Date of Acceptance: 20-Jan-2014
URI: http://hdl.handle.net/10044/1/28744
DOI: https://dx.doi.org/10.1371/journal.pgen.1004235
ISSN: 1553-7390
Publisher: Public Library of Science
Journal / Book Title: PLOS Genetics
Volume: 10
Issue: 4
Copyright Statement: This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: G1002084
Keywords: Science & Technology
Life Sciences & Biomedicine
Genetics & Heredity
GENETICS & HEREDITY
GENOME-WIDE ASSOCIATION
ALLELIC EXPRESSION
GLYCEMIC TRAITS
RISK-FACTORS
LOCI
GENES
POPULATION
VARIANTS
GLUCOSE
METHYLATION
Alleles
Diabetes Mellitus, Type 2
Fasting
GRB10 Adaptor Protein
Genome-Wide Association Study
Glucose
Humans
Insulin
Insulin Resistance
Islets of Langerhans
Male
Middle Aged
Polymorphism, Single Nucleotide
Receptor, Insulin
Signal Transduction
Islets of Langerhans
Humans
Diabetes Mellitus, Type 2
Insulin Resistance
Insulin
Receptor, Insulin
Glucose
Fasting
Signal Transduction
Polymorphism, Single Nucleotide
Alleles
Middle Aged
Male
GRB10 Adaptor Protein
Genome-Wide Association Study
Science & Technology
Life Sciences & Biomedicine
Genetics & Heredity
GENETICS & HEREDITY
GENOME-WIDE ASSOCIATION
ALLELIC EXPRESSION
GLYCEMIC TRAITS
RISK-FACTORS
LOCI
GENES
POPULATION
VARIANTS
GLUCOSE
METHYLATION
Developmental Biology
0604 Genetics
Publication Status: Published
Article Number: e1004235
Appears in Collections:Faculty of Medicine
Epidemiology, Public Health and Primary Care



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