A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

Title: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
Author(s): Lehne, B
Drong, AW
Loh, M
Zhang, W
Scott, WR
Tan, S-T
Afzal, U
Scott, J
Jarvelin, M-R
Elliott, P
McCarthy, MI
Kooner, JS
Chambers, JC
Item Type: Journal Article
Publication Date: 15-Feb-2015
Date of Acceptance: 28-Jan-2015
URI: http://hdl.handle.net/10044/1/28695
DOI: https://dx.doi.org/10.1186/s13059-015-0600-x
ISSN: 1474-760X
Publisher: BioMed Central
Journal / Book Title: Genome Biology
Volume: 16
Sponsor/Funder: Medical Research Council (MRC)
Medical Research Council (MRC)
Funder's Grant Number: G0700931
G0601966
Copyright Statement: © 2015 Lehne et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
Genetics & Heredity
METHYLATION ARRAY DATA
DNA METHYLATION
QUANTILE NORMALIZATION
PANCREATIC-ISLETS
PERIPHERAL-BLOOD
SUBSET-QUANTILE
GENE-EXPRESSION
MICROARRAY
PIPELINE
CANCER
CpG Islands
DNA Methylation
Epigenesis, Genetic
Epigenomics
Genome, Human
Genome-Wide Association Study
Humans
Oligonucleotide Array Sequence Analysis
Quantitative Trait Loci
Software
Humans
Oligonucleotide Array Sequence Analysis
DNA Methylation
Epigenesis, Genetic
CpG Islands
Quantitative Trait Loci
Genome, Human
Software
Genome-Wide Association Study
Epigenomics
Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
Genetics & Heredity
METHYLATION ARRAY DATA
DNA METHYLATION
QUANTILE NORMALIZATION
PANCREATIC-ISLETS
PERIPHERAL-BLOOD
SUBSET-QUANTILE
GENE-EXPRESSION
MICROARRAY
PIPELINE
CANCER
Bioinformatics
05 Environmental Sciences
06 Biological Sciences
08 Information And Computing Sciences
Publication Status: Published
Article Number: 37
Appears in Collections:Faculty of Medicine
Epidemiology, Public Health and Primary Care



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