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Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in beta-adrenergic signaling and enhances apoptosis

Title: Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in beta-adrenergic signaling and enhances apoptosis
Authors: Roca-Alonso, L
Castellano, L
Mills, A
Dabrowska, AF
Sikkel, MB
Pellegrino, L
Jacob, J
Frampton, AE
Krell, J
Coombes, RC
Harding, SE
Lyon, AR
Stebbing, J
Item Type: Journal Article
Issue Date: 1-May-2015
Date of Acceptance: 12-Jan-2015
URI: http://hdl.handle.net/10044/1/28657
DOI: https://dx.doi.org/10.1038/cddis.2015.89
ISSN: 2041-4889
Publisher: Nature Publishing Group
Journal / Book Title: Cell Death & Disease
Volume: 6
Copyright Statement: Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Sponsor/Funder: British Heart Foundation
British Heart Foundation
National Institute for Health Research
Cancer Research UK
Funder's Grant Number: RE/08/002
FS/11/67/28954
NIHR-RP-011-053
C27532/A14549
Keywords: Science & Technology
Life Sciences & Biomedicine
Cell Biology
HEART-FAILURE
CELL-DEATH
CARDIAC-HYPERTROPHY
BREAST-CANCER
IN-VIVO
FAILING HUMAN
CYTOCHROME-C
RAT-HEART
G-PROTEIN
CARDIOMYOPATHY
Publication Status: Published
Article Number: e1754
Appears in Collections:Division of Surgery
National Heart and Lung Institute
Division of Cancer
Faculty of Medicine



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