Power Loss Mechanisms in Pathological Tracheas

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Title: Power Loss Mechanisms in Pathological Tracheas
Authors: Bates, A
Comerford, A
Cetto, R
Schroter, R
Tolley, N
Doorly, D
Item Type: Journal Article
Abstract: The effort required to inhale a breath of air is a critically important measure in assessing airway function. Although the contribution of the trachea to the total flow resistance of the airways is generally modest, pathological alterations in tracheal geometry can have a significant negative effect. This study investigates the mechanisms of flow energy loss in a healthy trachea and in four geometries affected by retrosternal goitre which can cause significant distortions of tracheal geometry including constriction and deviation with abnormal curvature. By separating out the component of energy loss related to the wall shear (frictional loss), striking differences are found between the patterns of energy dissipation in the normal and pathological tracheas. Furthermore the ratio of frictional to total loss is dramatically reduced in the pathological geometries.
Issue Date: 30-Nov-2015
Date of Acceptance: 1-Oct-2015
URI: http://hdl.handle.net/10044/1/28097
DOI: https://dx.doi.org/10.1016/j.jbiomech.2015.11.033
ISSN: 1873-2380
Publisher: Elsevier
Start Page: 2187
End Page: 2192
Journal / Book Title: Journal of Biomechanics
Volume: 49
Issue: 11
Copyright Statement: © 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Sponsor/Funder: Engineering & Physical Science Research Council (EPSRC)
Funder's Grant Number: N/A
Keywords: Airflow
Work of breathing
Work of breathing
Biomedical Engineering
0903 Biomedical Engineering
1106 Human Movement And Sports Science
0913 Mechanical Engineering
Publication Status: Published
Appears in Collections:Faculty of Engineering

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