Design, conduct, and analysis of a multicenter, pharmacogenomic, biomarker study in matched patients with severe sepsis treated with or without drotrecogin Alfa (activated)

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Title: Design, conduct, and analysis of a multicenter, pharmacogenomic, biomarker study in matched patients with severe sepsis treated with or without drotrecogin Alfa (activated)
Authors: Annane, D
Mira, JP
Ware, LB
Gordon, AC
Sevransky, J
Stüber, F
Heagerty, PJ
Wellman, HF
Neira, M
Mancini, AD
Russell, JA
Item Type: Journal Article
Issue Date: 1-Jan-2012
URI: http://hdl.handle.net/10044/1/10020
DOI: http://dx.doi.org/10.1186/2110-5820-2-15
ISSN: 2110-5820
Publisher: Springer
Start Page: 15
End Page: 15
Journal / Book Title: Annals of intensive care
Volume: 2
Copyright Statement: © 2012 annane et al.; licensee Springer. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Notes: affiliation: Service de reanimation medicale, CIC-IT805 (INSERM), Hopital R, Poincare (AP-HP), 104 Bd Raymond Poincare, 92380, Garches, France. djillali.annane@rpc.aphp.fr. keywords: Sepsis, Drotrecogin alfa activated (DAA), Survival, Pharmacogenomics biomarker, Drotrecogin alfa (activated), Predictive marker, Severe sepsis, Propensity score, Activated protein C, Treatment selection, Genome wide association study date-added: 2012-08-05 15:28:56 +0100 date-modified: 2012-08-05 15:29:11 +0100 pmid: 22694772 local-url: file://localhost/Users/ag77/Documents/Papers/2012/Annane/Annals%20of%20intensive%20care%202012%20AnnaneDesign%20conduct%20and%20analysis%20of.pdf uri: papers://DDCB90E7-B2EE-42AF-9A24-AE61932E3D7E/Paper/p8523 rating: 0
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