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Remote multimodality monitoring of maternal physiology from the first trimester to postpartum period: study results.

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Title: Remote multimodality monitoring of maternal physiology from the first trimester to postpartum period: study results.
Authors: Zielinska, AP
Mullins, E
Magni, E
Zamagni, G
Kleprlikova, H
Adams, O
Stampalija, T
Monasta, L
Lees, C
Item Type: Journal Article
Abstract: OBJECTIVES: Current antenatal care largely relies on widely spaced appointments, hence only a fraction of the pregnancy period is subject to monitoring. Continuous monitoring of physiological parameters could represent a paradigm shift in obstetric care. Here, we analyse the data from daily home monitoring in pregnancy and consider the implications of this approach for tracking pregnancy health. METHODS: Prospective feasibility study of continuous home monitoring of blood pressure, weight, heart rate, sleep and activity patterns from the first trimester to 6 weeks postpartum. RESULTS: Fourteen out of 24 women completed the study (58%). Compared to early pregnancy [week 13, median heart rate (HR) 72/min, interquartile range (IQR) 12.8], heart rate increased by week 35 (HR 78/min, IQR 16.6; P = 0.041) and fell postpartum (HR 66/min, IQR 11.5, P = 0.021). Both systolic and diastolic blood pressure were lower at mid-gestation (week 20: SBP 103 mmHg, IQR 6.6; DPB 63 mmHg, IQR 5.3 P = 0.005 and P = 0.045, respectively) compared to early pregnancy (week 13, SBP 107 mmHg, IQR 12.4; DPB 67 mmHg, IQR 7.1). Weight increased during pregnancy between each time period analyzed, starting from week 15. Smartwatch recordings indicated that activity increased in the prepartum period, while deep sleep declined as pregnancy progressed. CONCLUSION: Home monitoring tracks individual physiological responses to pregnancy in high resolution that routine clinic visits cannot. Changes in the study protocol suggested by the study participants may improve compliance for future studies, which was particularly low in the postpartum period. Future work will investigate whether distinct adaptative patterns predate obstetric complications, or can predict long-term maternal cardiovascular health.
Issue Date: Nov-2022
Date of Acceptance: 1-Aug-2022
URI: http://hdl.handle.net/10044/1/99296
DOI: 10.1097/HJH.0000000000003260
ISSN: 0263-6352
Publisher: Lippincott, Williams & Wilkins
Start Page: 2280
End Page: 2291
Journal / Book Title: Journal of Hypertension
Volume: 40
Issue: 11
Copyright Statement: © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Cardiovascular System & Hematology
1102 Cardiorespiratory Medicine and Haematology
1103 Clinical Sciences
1116 Medical Physiology
Publication Status: Published
Conference Place: England
Open Access location: https://journals.lww.com/jhypertension/Fulltext/9900/Remote_multimodality_monitoring_of_maternal.82.aspx
Online Publication Date: 2022-08-16
Appears in Collections:Department of Metabolism, Digestion and Reproduction
Faculty of Medicine

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