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Assessing a sustainable manufacturing route to lapatinib
| File | Description | Size | Format | |
|---|---|---|---|---|
 d2re00267a.pdf | Published version | 397.4 kB | Adobe PDF | View/Open |
| Title: | Assessing a sustainable manufacturing route to lapatinib |
| Authors: | Stark, RT Pye, D Chen, W Newton, OJ Deadman, BJ Miller, P Panayides, J-L Riley, DL Hellgardt, K Hii, KKM |
| Item Type: | Journal Article |
| Abstract: | A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction. |
| Issue Date: | 9-Aug-2022 |
| Date of Acceptance: | 5-Aug-2022 |
| URI: | http://hdl.handle.net/10044/1/99067 |
| DOI: | 10.1039/d2re00267a |
| ISSN: | 2058-9883 |
| Publisher: | Royal Society of Chemistry |
| Start Page: | 2420 |
| End Page: | 2426 |
| Journal / Book Title: | Reaction Chemistry and Engineering |
| Volume: | 7 |
| Issue: | 11 |
| Copyright Statement: | © The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. |
| Keywords: | Science & Technology Physical Sciences Technology Chemistry, Multidisciplinary Engineering, Chemical Chemistry Engineering INHIBITORS EGFR |
| Publication Status: | Published |
| Online Publication Date: | 2022-08-09 |
| Appears in Collections: | Chemistry Catalysis and Advanced Materials Chemical Engineering Faculty of Natural Sciences Faculty of Engineering |
This item is licensed under a Creative Commons License
