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Trends in prevalence, mortality, and disability-adjusted life-years relating to chronic obstructive pulmonary disease in Europe: an observational study of the global burden of disease database, 2001-2019

Title: Trends in prevalence, mortality, and disability-adjusted life-years relating to chronic obstructive pulmonary disease in Europe: an observational study of the global burden of disease database, 2001-2019
Authors: Marshall, DC
Al Omari, O
Goodall, R
Shalhoub, J
Adcock, IM
Chung, KF
Salciccioli, JD
Item Type: Journal Article
Abstract: Introduction Chronic Obstructive Pulmonary Disease (COPD) is associated with significant mortality and well-defined aetiological factors. Previous reports indicate that mortality from COPD is falling worldwide. This study aims to assess the burden of COPD using prevalence, mortality, and disability-adjusted life years (DALYs) between 2001 and 2019 in 28 European countries (the European Union and the United Kingdom). Methods We extracted COPD data from the Global Burden of Disease database based on the International Classification of Diseases versions 10 (J41, 42, 43, 44 and 47). Age-standardised prevalence rates (ASPRs), age-standardised mortality rates (ASMRs), and DALYs were analysed for European countries by sex for each year (2001–2019) and reported per 100,000 population. We used Joinpoint regression analysis to quantify changing trends in the burden of COPD. Results In 2019, the median ASPR across Europe was 3230/100,000 for males and 2202/100,000 for females. Between 2001 and 2019, the median percentage change in ASPR was − 9.7% for males and 4.3% for females. 23/28 countries demonstrated a decrease in ASPRs in males, and 11/28 demonstrated a decrease in females. The median percentage change in ASMR between 2001 and 2019 was − 27.5% for males and − 10.4% for females. 25/28 and 19/28 countries demonstrated a decrease in ASMR in males and females, respectively. Conclusion In the EU between 2001 and 2019 COPD prevalence has overall increased in females but continues to decrease in males and in some countries, female prevalence now exceeds that of males. COPD mortality in the EU has decreased overall between 2001 and 2019; however, this decrease is not universal, particularly in females, and therefore remains a substantial source of amenable mortality.
Issue Date: 28-Jul-2022
Date of Acceptance: 8-Jul-2022
URI: http://hdl.handle.net/10044/1/99005
DOI: 10.1186/s12890-022-02074-z
ISSN: 1471-2466
Publisher: BioMed Central
Journal / Book Title: BMC Pulmonary Medicine
Volume: 22
Issue: 1
Copyright Statement: © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Keywords: Science & Technology
Life Sciences & Biomedicine
Respiratory System
Chronic obstructive pulmonary disease
COPD
Mortality
Prevalence
Trends
JOINPOINT REGRESSION
AIR-POLLUTION
COPD
Chronic obstructive pulmonary disease
Mortality
Prevalence
Trends
Disability-Adjusted Life Years
Europe
Female
Global Burden of Disease
Humans
Male
Prevalence
Pulmonary Disease, Chronic Obstructive
Quality-Adjusted Life Years
Risk Factors
Humans
Pulmonary Disease, Chronic Obstructive
Prevalence
Risk Factors
Quality-Adjusted Life Years
Europe
Female
Male
Global Burden of Disease
Disability-Adjusted Life Years
Science & Technology
Life Sciences & Biomedicine
Respiratory System
Chronic obstructive pulmonary disease
COPD
Mortality
Prevalence
Trends
JOINPOINT REGRESSION
AIR-POLLUTION
1102 Cardiorespiratory Medicine and Haematology
Respiratory System
Publication Status: Published
Article Number: ARTN 289
Appears in Collections:Department of Surgery and Cancer
National Heart and Lung Institute
Faculty of Medicine



This item is licensed under a Creative Commons License Creative Commons