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Polymorphic microbes: a new emerging hallmark of cancer

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Title: Polymorphic microbes: a new emerging hallmark of cancer
Authors: Lythgoe, MP
Mullish, BH
Frampton, A
Krell, J
Item Type: Journal Article
Abstract: Recognition of the microbiome (and ‘polymorphic microbes’ within them) as a new emerging hallmark of cancer reflects a wide body of rapidly evolving research. Microbes may be directly carcinogenic, impact host immune responses to promote malignancy, and key effectors in determining anti-cancer therapy efficacy. Manipulation of the microbiome is showing promise as an opportunity to influence cancer outcomes.
Issue Date: Dec-2022
Date of Acceptance: 3-Aug-2022
URI: http://hdl.handle.net/10044/1/98973
DOI: 10.1016/j.tim.2022.08.004
ISSN: 0966-842X
Publisher: Cell Press
Start Page: 1131
End Page: 1134
Journal / Book Title: Trends in Microbiology
Volume: 30
Issue: 12
Copyright Statement: © 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Sponsor/Funder: Imperial College Healthcare NHS Trust- BRC Funding
4D Pharma Plc
Ovarian Cancer Action
Funder's Grant Number: RDA02
C/35/2017
n/a
Keywords: cancer hallmarks
faecal microbiota transplantation
gut microbiome
intratumoural microbiome
live biotherapeutic
polymorphic microbes
Humans
Gastrointestinal Microbiome
Microbiota
Neoplasms
Humans
Neoplasms
Microbiota
Gastrointestinal Microbiome
Microbiology
0605 Microbiology
1108 Medical Microbiology
Publication Status: Published
Online Publication Date: 2022-09-01
Appears in Collections:Department of Metabolism, Digestion and Reproduction
Department of Surgery and Cancer
Faculty of Medicine



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