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A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants

Title: A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants
Authors: Burge, T
Jeffers, J
Myant, C
Item Type: Journal Article
Abstract: A methodology to explore the design space of off-the-shelf total knee replacement implant designs is outlined. Generic femur component and tibia plate designs were scaled to thousands of sizes and virtually fitted to 244 test subjects. Various implant designs and sizing requirements between genders and ethnicities were evaluated. 5 sizes optimised via the methodology produced a good global fit for most subjects. However, clinically significant over/underhang was present in 19% of subjects for tibia plates and 25% for femur components, reducing to 11/20% with 8 sizes. The analysis highlighted subtly better fit performance was obtained using sizes with unequal spacing.
Issue Date: 1-May-2023
Date of Acceptance: 5-May-2022
URI: http://hdl.handle.net/10044/1/97288
DOI: 10.1080/10255842.2022.2075224
ISSN: 1025-5842
Publisher: Taylor and Francis
Start Page: 629
End Page: 638
Journal / Book Title: Computer Methods in Biomechanics and Biomedical Engineering
Volume: 26
Issue: 6
Copyright Statement: © 2022 Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
Publication Status: Published
Online Publication Date: 2022-05-13
Appears in Collections:Mechanical Engineering
Dyson School of Design Engineering
Faculty of Engineering



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