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JMM Profile: Actinobacillus pleuropneumoniae: a major cause of lung disease in pigs but difficult to control and eradicate

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Title: JMM Profile: Actinobacillus pleuropneumoniae: a major cause of lung disease in pigs but difficult to control and eradicate
Authors: Stringer, O
Li, Y
Bosse, J
Langford, P
Item Type: Journal Article
Abstract: The Gram-negative bacterium Actinobacillus pleuropneumoniae is the causative agent of pleuropneumonia in pigs, its only known natural host. Typical symptoms of peracute disease include fever, apathy and anorexia, and time from infection to death may only be 6 h. Severe lung lesions result from presence of one or two of the ApxI-III toxins. Control is through good husbandry practice, vaccines and antibiotic use. Culture and presence of the species-specific apxIV gene by PCR confirms diagnosis, and identification of serovar, of which 19 are known, informs on appropriate vaccine use and epidemiology.
Issue Date: 1-Mar-2022
Date of Acceptance: 19-Nov-2021
URI: http://hdl.handle.net/10044/1/95371
DOI: 10.1099/jmm.0.001483
ISSN: 0022-2615
Publisher: Microbiology Society
Journal / Book Title: Journal of Medical Microbiology
Volume: 71
Issue: 3
Copyright Statement: © 2022 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
Sponsor/Funder: Biotechnology and Biological Sciences Research Council (BBSRC)
Biotechnology and Biological Sciences Research Council
Biotechnology and Biological Sciences Research Council (BBSRC)
Ceva Sante Animale
Funder's Grant Number: BB/S002103/1
BB/S019901/1
BB/S005897/1
1126797
Keywords: Microbiology
06 Biological Sciences
07 Agricultural and Veterinary Sciences
11 Medical and Health Sciences
Publication Status: Published
Article Number: ARTN 001483
Online Publication Date: 2022-03-09
Appears in Collections:Department of Infectious Diseases



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