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Influence of material deprivation on clinical outcomes among people living with HIV in high-income countries: a systematic review and meta-analysis

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Title: Influence of material deprivation on clinical outcomes among people living with HIV in high-income countries: a systematic review and meta-analysis
Authors: Papageorgiou, V
Davies, B
Cooper, E
Singer, A
Ward, H
Item Type: Journal Article
Abstract: Despite developments in HIV treatment and care, disparities persist with some not fully benefiting from improvements in the HIV care continuum. We conducted a systematic review to explore associations between social determinants and HIV treatment outcomes (viral suppression and treatment adherence) in high-income countries. A random effects meta-analysis was performed where there were consistent measurements of exposures. We identified 83 observational studies eligible for inclusion. Social determinants linked to material deprivation were identified as education, employment, food security, housing, income, poverty/deprivation, socioeconomic status/position, and social class; however, their measurement and definition varied across studies. Our review suggests a social gradient of health persists in the HIV care continuum; people living with HIV who reported material deprivation were less likely to be virologically suppressed or adherent to antiretrovirals. Future research should use an ecosocial approach to explore these interactions across the lifecourse to help propose a causal pathway.
Issue Date: 1-Jun-2022
Date of Acceptance: 27-Nov-2021
URI: http://hdl.handle.net/10044/1/93162
DOI: 10.1007/s10461-021-03551-y
ISSN: 1090-7165
Publisher: Springer
Start Page: 2026
End Page: 2054
Journal / Book Title: AIDS and Behavior
Volume: 26
Copyright Statement: © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Sponsor/Funder: Economic and Social Research Council
Keywords: Science & Technology
Social Sciences
Life Sciences & Biomedicine
Public, Environmental & Occupational Health
Social Sciences, Biomedical
Biomedical Social Sciences
Antiretroviral therapy
HIV
Meta-analysis
Social determinants of health
Socioeconomic factors
Systematic review
Viral suppression
ACTIVE ANTIRETROVIRAL THERAPY
HUMAN-IMMUNODEFICIENCY-VIRUS
WHITE HIV/AIDS PROGRAM
INTIMATE PARTNER VIOLENCE
VIRAL LOAD SUPPRESSION
INFECTED PATIENTS
SOCIAL DETERMINANTS
TRANSGENDER WOMEN
MEDICATION ADHERENCE
VIROLOGICAL RESPONSE
Antiretroviral therapy
HIV
Meta-analysis
Social determinants of health
Socioeconomic factors
Systematic review
Viral suppression
Anti-Retroviral Agents
Developed Countries
HIV Infections
Humans
Income
Poverty
Humans
HIV Infections
Anti-Retroviral Agents
Developed Countries
Poverty
Income
1117 Public Health and Health Services
1607 Social Work
Public Health
Publication Status: Published
Online Publication Date: 2021-12-11
Appears in Collections:Faculty of Medicine
School of Public Health



This item is licensed under a Creative Commons License Creative Commons