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Lessons of the month 3: Spontaneous resolution of frontotemporal brain sagging syndrome.

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Title: Lessons of the month 3: Spontaneous resolution of frontotemporal brain sagging syndrome.
Authors: Kent, L
Butterworth, R
Butler, C
Item Type: Journal Article
Abstract: We present a case of a man with headache and progressive behavioural disturbance. His cognitive decline progressed over a few months such that he was unable to hold a conversation or carry out any daily tasks such as washing and dressing. He had some upper motor neurone signs in his limbs and features of brainstem dysfunction including dysarthria and ocular abnormalities. His brain magnetic resonance imaging showed signs of brain 'sagging'. He was thought to have frontotemporal brain sagging syndrome. Prior to any treatment, he began to improve. Over the course of a week he became markedly better, was back to normal within 3 months and remains so 7 months later. We propose that resolution of spontaneous intracranial hypotension led to resolution of frontotemporal brain sagging syndrome. We believe this is the first case described where this has occurred without any intervention. It is important to recognise this condition as a potentially reversible cause of dementia.
Issue Date: Jul-2019
Date of Acceptance: 1-Jul-2019
URI: http://hdl.handle.net/10044/1/91177
DOI: 10.7861/clinmedicine.19-4-336
ISSN: 1470-2118
Publisher: Royal College of Physicians
Start Page: 336
End Page: 337
Journal / Book Title: Clinical medicine (London, England)
Volume: 19
Issue: 4
Copyright Statement: © Royal College of Physicians 2019. All rights reserved.
Keywords: CSF dynamics
Frontotemporal dementia
low pressure headache
Brain
Frontotemporal Dementia
Humans
Intracranial Hypotension
Magnetic Resonance Imaging
Male
Middle Aged
Remission, Spontaneous
Brain
Humans
Intracranial Hypotension
Magnetic Resonance Imaging
Remission, Spontaneous
Middle Aged
Male
Frontotemporal Dementia
CSF dynamics
Frontotemporal dementia
low pressure headache
Brain
Frontotemporal Dementia
Humans
Intracranial Hypotension
Magnetic Resonance Imaging
Male
Middle Aged
Remission, Spontaneous
General Clinical Medicine
1103 Clinical Sciences
Publication Status: Published
Conference Place: England
Open Access location: https://www.rcpjournals.org/content/clinmedicine/19/4/336
Online Publication Date: 2019-07-15
Appears in Collections:Department of Brain Sciences