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Under-reporting of known HIV-positive status among people living with HIV: a systematic review and meta-analysis

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Title: Under-reporting of known HIV-positive status among people living with HIV: a systematic review and meta-analysis
Authors: Soni, N
Giguère, K
Boily, M-C
Fogel, JM
Maheu-Giroux, M
Dimitrov, D
Eshleman, SH
Mitchell, K
Item Type: Journal Article
Abstract: Monitoring progress towards the UNAIDS ‘first 90’ target requires accurate estimates of levels of diagnosis among people living with HIV (PLHIV), which is often estimated using self-report. We conducted a systematic review and meta-analysis quantifying under-reporting of known HIV-positive status using objective knowledge proxies. Databases were searched for studies providing self-reported and biological/clinical markers of prior knowledge of HIV-positive status among PLHIV. Random-effects models were used to derive pooled estimates of levels of under-reporting. Thirty-two estimates from 26 studies were included (41,465 PLHIV). The pooled proportion under-reporting known HIV-positive status was 20% (95% confidence interval 13–26%, I2 = 99%). In sub-group analysis, under-reporting was higher among men who have sex with men (32%, number of estimates [Ne] = 10) compared to the general population (9%, Ne = 10) and among Black (18%, Ne = 5) than non-Black (3%, Ne = 3) individuals. Supplementing self-reported data with biological/clinical proxies may improve the validity of the ‘first 90’ estimates.
Issue Date: 28-May-2021
Date of Acceptance: 11-May-2021
URI: http://hdl.handle.net/10044/1/89769
DOI: 10.1007/s10461-021-03310-z
ISSN: 1090-7165
Publisher: Springer
Journal / Book Title: AIDS and Behavior
Copyright Statement: © The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Sponsor/Funder: National Institutes of Health
Funder's Grant Number: UM1AI068617 Sub#0001014222
Keywords: Bias
HIV status
Public Health
1117 Public Health and Health Services
1607 Social Work
Publication Status: Published online
Online Publication Date: 2021-05-28
Appears in Collections:Faculty of Medicine
School of Public Health

This item is licensed under a Creative Commons License Creative Commons