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Resurgence of SARS-CoV-2: detection by community viral surveillance

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Title: Resurgence of SARS-CoV-2: detection by community viral surveillance
Authors: Riley, S
Ainslie, KEC
Eales, O
Walters, CE
Wang, H
Atchison, C
Fronterre, C
Diggle, PJ
Ashby, D
Donnelly, CA
Cooke, G
Barclay, W
Ward, H
Darzi, A
Elliott, P
Item Type: Journal Article
Abstract: Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.
Issue Date: 28-May-2021
Date of Acceptance: 20-Apr-2021
URI: http://hdl.handle.net/10044/1/89736
DOI: 10.1126/science.abf0874
ISSN: 0036-8075
Publisher: American Association for the Advancement of Science
Start Page: 990
End Page: 995
Journal / Book Title: Science
Volume: 372
Issue: 6545
Copyright Statement: © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: National Institute for Health Research
National Institute for Health Research
UK Research and Innovation
Funder's Grant Number: RDB21 79560
RP-2016-07-012
9815274 MC_PC_19025
Keywords: Adolescent
Adult
Aged
Basic Reproduction Number
COVID-19
COVID-19 Nucleic Acid Testing
Child
Child, Preschool
England
Epidemiological Monitoring
Female
Humans
Male
Middle Aged
Pandemics
Prevalence
Public Health Surveillance
SARS-CoV-2
Young Adult
Humans
Prevalence
Adolescent
Adult
Aged
Middle Aged
Child
Child, Preschool
England
Female
Male
Basic Reproduction Number
Young Adult
Pandemics
Epidemiological Monitoring
Public Health Surveillance
COVID-19
SARS-CoV-2
COVID-19 Nucleic Acid Testing
Adolescent
Adult
Aged
Basic Reproduction Number
COVID-19
COVID-19 Nucleic Acid Testing
Child
Child, Preschool
England
Epidemiological Monitoring
Female
Humans
Male
Middle Aged
Pandemics
Prevalence
Public Health Surveillance
SARS-CoV-2
Young Adult
General Science & Technology
Publication Status: Published
Conference Place: United States
Open Access location: https://science.sciencemag.org/content/372/6545/990
Online Publication Date: 2021-04-23
Appears in Collections:Department of Surgery and Cancer
Department of Infectious Diseases
Institute of Global Health Innovation
Imperial College London COVID-19
School of Public Health



This item is licensed under a Creative Commons License Creative Commons