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Chronic airflow obstruction and ambient particulate air pollution

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Title: Chronic airflow obstruction and ambient particulate air pollution
Authors: Amaral, A
Burney, P
Patel, J
Minelli, C
Mejza, F
Mannino, D
Seemungal, T
Padukudru Anand, M
Loh, LC
Janson, C
Juvekar, S
Denguezli, M
Harrabi, I
Wouters, E
Cherkaski, H
Mortimer, K
Jogi, R
Bateman, E
Fuertes, E
Al Ghobain, M
Tan, W
Obaseki, D
El Sony, A
Studnicka, M
Aquart-Stewart, A
Koul, P
Lawin, H
Nafees, A
Awopeju, O
Erhabor, G
Gislason, T
Welte, T
Gulsvik, A
Nielsen, R
Gnatiuc, L
Kocabas, A
Marks, G
Sooronbaev, T
Mbatchou Ngahane, B
Barbara, C
Buist, AS
Item Type: Journal Article
Abstract: Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.
Issue Date: 11-May-2021
Date of Acceptance: 9-Apr-2021
URI: http://hdl.handle.net/10044/1/89493
DOI: 10.1136/thoraxjnl-2020-216223
ISSN: 0040-6376
Publisher: BMJ Publishing Group
Journal / Book Title: Thorax
Copyright Statement: © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
Sponsor/Funder: Wellcome Trust
Funder's Grant Number: 085790/Z/08/Z
Keywords: COPD epidemiology
BOLD (Burden of Obstructive Lung Disease) Collaborative Research Group
BOLD (Burden of Obstructive Lung Disease) Collaborative Research Group members
Respiratory System
1103 Clinical Sciences
Publication Status: Published online
Online Publication Date: 2021-05-11
Appears in Collections:Department of Infectious Diseases
National Heart and Lung Institute



This item is licensed under a Creative Commons License Creative Commons