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Point-of-Care Haemoglobin testing in African hospitals: a neglected essential diagnostic test

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Title: Point-of-Care Haemoglobin testing in African hospitals: a neglected essential diagnostic test
Authors: Uyoga, S
George, EC
Bates, I
Olupot-Olupot, P
Chimalizeni, Y
Molyneux, EM
Maitland, K
Item Type: Journal Article
Abstract: Owing to the rapid turnaround time in the assessment of haemoglobin level by point-of-care (POC) tests, it has grown in popularity and scope in large parts of the world. However, whilst POC testing for malaria and HIV remains has been integrated into patient management in Africa, the use of POC haemoglobin testing has remains neglected by health services. The main users of transfusions (paediatric, maternity and trauma services) present largely as emergencies. Ward-based POCHb could result in more rapid and accurate diagnosis of anaemia, contributing to saving of lives and at the same time reduce unnecessary transfusions which deplete the limited supplies of donated blood in Africa. Severe anaemia requiring transfusion is a major cause of paediatric admission in Africa. A dissemination meeting to discuss the results of a large phase III paediatric transfusion trial and steps to implementation of the findings members strongly recommended that one of the most pressing actions required was to prioritise the use of POC haemoglobin testing. This would facilitate implementation of the new transfusion algorithm, developed at the meeting which refine patient management including blood transfusions. We present the rationale for strongly recommended prioritization of POCHb, using paediatric transfusion as an examplar.
Issue Date: Jun-2021
Date of Acceptance: 2-Mar-2021
URI: http://hdl.handle.net/10044/1/88469
DOI: 10.1111/bjh.17431
ISSN: 0007-1048
Publisher: Wiley
Start Page: 894
End Page: 901
Journal / Book Title: British Journal of Haematology
Volume: 193
Issue: 5
Copyright Statement: © 2021 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: Medical Research Council (MRC)
Medical Research Council
Medical Research Council
Funder's Grant Number: MR/J012483/1
MR/J012483/1
MR/J012483/1
Keywords: Science & Technology
Life Sciences & Biomedicine
Hematology
anaemia in developing world
diagnostic haematology
transfusion medicine
paediatric anaemia
children
SUB-SAHARAN AFRICA
SEVERE ANEMIA
BLOOD-TRANSFUSION
CLINICAL PALLOR
CHILDREN
HEMATOCRIT
TRENDS
anaemia in developing world
children
diagnostic haematology
paediatric anaemia
transfusion medicine
1102 Cardiorespiratory Medicine and Haematology
Immunology
Publication Status: Published
Online Publication Date: 2021-05-15
Appears in Collections:Department of Surgery and Cancer
Department of Infectious Diseases
Faculty of Medicine



This item is licensed under a Creative Commons License Creative Commons