Folate deficiency after Bariatric surgery; A CPRD study

Title: Folate deficiency after Bariatric surgery; A CPRD study
Authors: Moussa, O
Arhi, C
Adrissino, M
Khan, O
Ziprin, P
Darzi, A
Purkayastha, S
Item Type: Conference Paper
Abstract: Background: Folate deficiency bariatric procedures that can contribute to anemia. The prevalence of this deficit after both restrictive and malabsorptive procedures ranges from 9% to 39% in the literature. Our aim was to interrogate the Clinical Practice Research Datalink (CPRD) for folate recordings in this surgical cohort. Method: All patients captured within the CPRD that had Bariatric surgery episodes were interrogated to assess folate level measurements using SPSS 25. Results: There were a total of 6,601 recorded folate measurements for 4414 patients in the bariatric surgery group within the CPRD. There were 1,710(25.9%) recordings pre-operatively and 4,891(74.1%) postoperatively. 31.9% had recordings pre and post-operatively. Readings ranged from 1 to 23 (4.22,SD 4.32) and 1 to 46 (5.87,SD 6.20) post-operatively. Folate was low in 173(10.1%) patients and high in 81 (4.7%) patients prior, while 408(8.3%) and 475 (9.7%) after surgery respectively. Bariatric surgery had a significant effect on the difference of low (p=0.029) and high (p<0.001) folate levels from pre to post-operative. Folate recordings averaged 45.90 months. OBES SURG (2020) 30 (Suppl 1):S1–S78 S55 Conclusion: Folate is well documented in the Bariatric surgery cohort within the CPRD, measurements are documented better postoperatively. Folate was abnormal in a minority pre and post-operatively, however there is a significant effect of Bariatric surgery on perioperative folate deficiencies.
Issue Date: 1-Mar-2020
Date of Acceptance: 1-Feb-2020
URI: http://hdl.handle.net/10044/1/88066
DOI: 10.1007/s11695-020-04433-3
ISSN: 0960-8923
Publisher: Springer
Start Page: S55
End Page: S56
Journal / Book Title: Obesity Surgery
Volume: 30
Issue: SUPPL 1
Sponsor/Funder: National Institute of Health Research
Conference Name: 11th Annual Scientific Meeting of the British-Obesity-and-Metabolic-Surgery-Society (BOMSS)
Keywords: Science & Technology
Life Sciences & Biomedicine
Surgery
Science & Technology
Life Sciences & Biomedicine
Surgery
Surgery
1103 Clinical Sciences
1117 Public Health and Health Services
Publication Status: Published
Start Date: 2020-01-23
Finish Date: 2020-01-24
Conference Place: Aberdeen, SCOTLAND
Open Access location: https://link.springer.com/article/10.1007/s11695-020-04433-3
Online Publication Date: 2020-02-17
Appears in Collections:Department of Surgery and Cancer
Institute of Global Health Innovation



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