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C3 glomerulopathy: consensus report

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Title: C3 glomerulopathy: consensus report
Authors: Pickering, MC
D'Agati, VD
Nester, CM
Smith, RJ
Haas, M
Appel, GB
Alpers, CE
Bajema, IM
Bedrosian, C
Braun, M
Doyle, M
Fakhouri, F
Fervenza, FC
Fogo, AB
Fremeaux-Bacchi, V
Gale, DP
De Jorge, EG
Griffin, G
Harris, CL
Holers, VM
Johnson, S
Lavin, PJ
Medjeral-Thomas, N
Morgan, BP
Nast, CC
Noel, L-H
Peters, DK
Rodriguez de Cordoba, S
Servais, A
Sethi, S
Song, W-C
Tamburini, P
Thurman, JM
Zavros, M
Cook, HT
Item Type: Journal Article
Abstract: C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.
Issue Date: 1-Dec-2013
Date of Acceptance: 20-Jun-2013
URI: http://hdl.handle.net/10044/1/87720
DOI: 10.1038/ki.2013.377
ISSN: 0085-2538
Publisher: Elsevier
Start Page: 1079
End Page: 1089
Journal / Book Title: Kidney International
Volume: 84
Issue: 6
Copyright Statement: © 2013 International Society of Nephrology. Published by Elsevier Inc. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
Sponsor/Funder: Wellcome Trust
Funder's Grant Number: 098476/Z/12/Z
Keywords: Science & Technology
Life Sciences & Biomedicine
Urology & Nephrology
clinical immunology
clinical nephrology
complement
glomerulonephritis
immunology and pathology
DENSE-DEPOSIT DISEASE
COMPLEMENT FACTOR-H
MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
PROVIDES INSIGHTS
ECULIZUMAB
MUTATION
CLASSIFICATION
DYSREGULATION
ACTIVATION
MECHANISM
Biomedical Research
Biopsy
Complement C3
Cooperative Behavior
Glomerulonephritis
Humans
International Cooperation
Kidney Glomerulus
Predictive Value of Tests
Prognosis
Kidney Glomerulus
Humans
Glomerulonephritis
Biopsy
Prognosis
Predictive Value of Tests
Cooperative Behavior
Biomedical Research
International Cooperation
Complement C3
Science & Technology
Life Sciences & Biomedicine
Urology & Nephrology
clinical immunology
clinical nephrology
complement
glomerulonephritis
immunology and pathology
DENSE-DEPOSIT DISEASE
COMPLEMENT FACTOR-H
MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
PROVIDES INSIGHTS
ECULIZUMAB
MUTATION
CLASSIFICATION
DYSREGULATION
ACTIVATION
MECHANISM
1103 Clinical Sciences
Urology & Nephrology
Publication Status: Published
Online Publication Date: 2015-12-16
Appears in Collections:Department of Immunology and Inflammation



This item is licensed under a Creative Commons License Creative Commons