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C3 glomerulopathy: consensus report
File | Description | Size | Format | |
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C3 glomerulopathy consensus report.pdf | Published version | 1.5 MB | Adobe PDF | View/Open |
Title: | C3 glomerulopathy: consensus report |
Authors: | Pickering, MC D'Agati, VD Nester, CM Smith, RJ Haas, M Appel, GB Alpers, CE Bajema, IM Bedrosian, C Braun, M Doyle, M Fakhouri, F Fervenza, FC Fogo, AB Fremeaux-Bacchi, V Gale, DP De Jorge, EG Griffin, G Harris, CL Holers, VM Johnson, S Lavin, PJ Medjeral-Thomas, N Morgan, BP Nast, CC Noel, L-H Peters, DK Rodriguez de Cordoba, S Servais, A Sethi, S Song, W-C Tamburini, P Thurman, JM Zavros, M Cook, HT |
Item Type: | Journal Article |
Abstract: | C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group. |
Issue Date: | 1-Dec-2013 |
Date of Acceptance: | 20-Jun-2013 |
URI: | http://hdl.handle.net/10044/1/87720 |
DOI: | 10.1038/ki.2013.377 |
ISSN: | 0085-2538 |
Publisher: | Elsevier |
Start Page: | 1079 |
End Page: | 1089 |
Journal / Book Title: | Kidney International |
Volume: | 84 |
Issue: | 6 |
Copyright Statement: | © 2013 International Society of Nephrology. Published by Elsevier Inc. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
Sponsor/Funder: | Wellcome Trust |
Funder's Grant Number: | 098476/Z/12/Z |
Keywords: | Science & Technology Life Sciences & Biomedicine Urology & Nephrology clinical immunology clinical nephrology complement glomerulonephritis immunology and pathology DENSE-DEPOSIT DISEASE COMPLEMENT FACTOR-H MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS PROVIDES INSIGHTS ECULIZUMAB MUTATION CLASSIFICATION DYSREGULATION ACTIVATION MECHANISM Biomedical Research Biopsy Complement C3 Cooperative Behavior Glomerulonephritis Humans International Cooperation Kidney Glomerulus Predictive Value of Tests Prognosis Kidney Glomerulus Humans Glomerulonephritis Biopsy Prognosis Predictive Value of Tests Cooperative Behavior Biomedical Research International Cooperation Complement C3 Science & Technology Life Sciences & Biomedicine Urology & Nephrology clinical immunology clinical nephrology complement glomerulonephritis immunology and pathology DENSE-DEPOSIT DISEASE COMPLEMENT FACTOR-H MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS PROVIDES INSIGHTS ECULIZUMAB MUTATION CLASSIFICATION DYSREGULATION ACTIVATION MECHANISM 1103 Clinical Sciences Urology & Nephrology |
Publication Status: | Published |
Online Publication Date: | 2015-12-16 |
Appears in Collections: | Department of Immunology and Inflammation |
This item is licensed under a Creative Commons License