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Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers

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Title: Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers
Authors: Pereira, C
Harris, B
Di Giovannantonio, M
Rosadas, C
Short, C-E
Quinlan, R
Sureda-Vives, M
Fernandez, N
Day-Weber, I
Khan, M
Marchesin, F
Katsanovskaja, K
Parker, E
Taylor, G
Tedder, R
McClure, M
Dani, M
Fertleman, M
Item Type: Journal Article
Abstract: It is currently unknown how Post-COVID-19 Syndrome (PCS) may affect those infected with SARS-CoV-2. This longitudinal study reports on healthcare staff who tested positive for SARS-CoV-2 between March-April 2020 and follows their antibody titres and symptomatology. Over half (n=21/38) had PCS at 7-8 months. There was no statistically significant difference between initial RT-PCR viral titres or serial antibody levels between those who did and did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers.
Issue Date: 28-Apr-2021
Date of Acceptance: 26-Feb-2021
URI: http://hdl.handle.net/10044/1/86255
DOI: 10.1093/infdis/jiab120
ISSN: 0022-1899
Publisher: Oxford University Press (OUP)
Start Page: 1671
End Page: 1676
Journal / Book Title: Journal of Infectious Diseases
Volume: 223
Issue: 10
Copyright Statement: © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords: COVID-19
Healthcare workers
Imperial Hybrid DABA
Post–COVID-19 Syndrome
multidisciplinary team
06 Biological Sciences
11 Medical and Health Sciences
Publication Status: Published
Online Publication Date: 2021-03-02
Appears in Collections:Bioengineering
Department of Infectious Diseases
Faculty of Medicine
Imperial College London COVID-19
Faculty of Engineering

This item is licensed under a Creative Commons License Creative Commons