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Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers
| File | Description | Size | Format | |
|---|---|---|---|---|
 jiab120.pdf | Published version | 2.2 MB | Adobe PDF | View/Open |
| Title: | Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers |
| Authors: | Pereira, C Harris, B Di Giovannantonio, M Rosadas, C Short, C-E Quinlan, R Sureda-Vives, M Fernandez, N Day-Weber, I Khan, M Marchesin, F Katsanovskaja, K Parker, E Taylor, G Tedder, R McClure, M Dani, M Fertleman, M |
| Item Type: | Journal Article |
| Abstract: | It is currently unknown how Post-COVID-19 Syndrome (PCS) may affect those infected with SARS-CoV-2. This longitudinal study reports on healthcare staff who tested positive for SARS-CoV-2 between March-April 2020 and follows their antibody titres and symptomatology. Over half (n=21/38) had PCS at 7-8 months. There was no statistically significant difference between initial RT-PCR viral titres or serial antibody levels between those who did and did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers. |
| Issue Date: | 28-Apr-2021 |
| Date of Acceptance: | 26-Feb-2021 |
| URI: | http://hdl.handle.net/10044/1/86255 |
| DOI: | 10.1093/infdis/jiab120 |
| ISSN: | 0022-1899 |
| Publisher: | Oxford University Press (OUP) |
| Start Page: | 1671 |
| End Page: | 1676 |
| Journal / Book Title: | Journal of Infectious Diseases |
| Volume: | 223 |
| Issue: | 10 |
| Copyright Statement: | © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| Keywords: | COVID-19 Healthcare workers Imperial Hybrid DABA Long-COVID Post–COVID-19 Syndrome SARS-CoV-2 multidisciplinary team Microbiology 06 Biological Sciences 11 Medical and Health Sciences |
| Publication Status: | Published |
| Online Publication Date: | 2021-03-02 |
| Appears in Collections: | Bioengineering Department of Infectious Diseases Faculty of Medicine Imperial College London COVID-19 Faculty of Engineering |
This item is licensed under a Creative Commons License
