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Reduction in mobility and COVID-19 transmission
File | Description | Size | Format | |
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s41467-021-21358-2.pdf | Published version | 1.79 MB | Adobe PDF | View/Open |
mobility_PNouvellet_NatCom_revision_SI.pdf | Supporting information | 10.91 MB | Adobe PDF | View/Open |
Title: | Reduction in mobility and COVID-19 transmission |
Authors: | Nouvellet, P Bhatia, S Cori, A Ainslie, K Baguelin, M Bhatt, S Boonyasiri, A Brazeau, N Cattarino, L Cooper, L Coupland, H Cucunuba Perez, Z Cuomo-Dannenburg, G Dighe, A Djaafara, A Dorigatti, I Eales, O Van Elsland, S NASCIMENTO, F Fitzjohn, R Gaythorpe, K Geidelberg, L Green, W Hamlet, A Hauck, K Hinsley, W Imai, N Jeffrey Jeffrey, B Knock, E Laydon, D Lees, J Mangal, T Mellan, T Nedjati Gilani, G Parag, K Pons Salort, M Ragonnet-Cronin, M Riley, S Unwin, H Verity, R Vollmer, M Volz, E Walker, P Walters, C Wang, H Watson, O Whittaker, C Whittles, L Xi, X Ferguson, N Donnelly, C |
Item Type: | Journal Article |
Abstract: | In response to the COVID-19 pandemic, countries have sought to control SARS-CoV-2 transmission by restricting population movement through social distancing interventions, thus reducing the number of contacts. Mobility data represent an important proxy measure of social distancing, and here, we characterise the relationship between transmission and mobility for 52 countries around the world. Transmission significantly decreased with the initial reduction in mobility in 73% of the countries analysed, but we found evidence of decoupling of transmission and mobility following the relaxation of strict control measures for 80% of countries. For the majority of countries, mobility explained a substantial proportion of the variation in transmissibility (median adjusted R-squared: 48%, interquartile range - IQR - across countries [27-77%]). Where a change in the relationship occurred, predictive ability decreased after the relaxation; from a median adjusted R-squared of 74% (IQR across countries [49-91%]) pre-relaxation, to a median adjusted R-squared of 30% (IQR across countries [12-48%]) post-relaxation. In countries with a clear relationship between mobility and transmission both before and after strict control measures were relaxed, mobility was associated with lower transmission rates after control measures were relaxed indicating that the beneficial effects of ongoing social distancing behaviours were substantial. |
Issue Date: | 17-Feb-2021 |
Date of Acceptance: | 12-Jan-2021 |
URI: | http://hdl.handle.net/10044/1/85559 |
DOI: | 10.1038/s41467-021-21358-2 |
ISSN: | 2041-1723 |
Publisher: | Nature Research |
Journal / Book Title: | Nature Communications |
Volume: | 12 |
Sponsor/Funder: | Medical Research Council (MRC) Medical Research Council (MRC) National Institute for Health Research International Society for Infectious Diseases Medical Research Council Wellcome Trust Medical Research Council Abdul Latif Jameel Foundation |
Funder's Grant Number: | MR/R015600/1 EP/V520354/1 NIHR200908 SBFF-2019-37324 MR/R015600/1 213494/Z/18/Z MR/R015600/1 |
Keywords: | Algorithms COVID-19 Communicable Disease Control Global Health Humans Models, Theoretical Pandemics Physical Distancing Quarantine SARS-CoV-2 Humans Communicable Disease Control Quarantine Algorithms Models, Theoretical Pandemics Global Health COVID-19 SARS-CoV-2 Physical Distancing |
Publication Status: | Published |
Article Number: | ARTN 1090 |
Appears in Collections: | Department of Infectious Diseases Faculty of Medicine School of Public Health |