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A review of portable high-performance liquid chromatography: the future of the field?

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Title: A review of portable high-performance liquid chromatography: the future of the field?
Authors: Rahimi, F
Chatzimichail, S
Saifuddin, A
Surman, A
Taylor-Robinson, S
Salehi-Reyhani, SA
Item Type: Journal Article
Abstract: There is a growing need for chemical analyses to be performed in the field, at the point of need. Tools and techniques often found in analytical chemistry laboratories are necessary in performing these analyses, yet have, historically, been unable to do so owing to their size, cost and complexity. Technical advances in miniaturisation and liquid chromatography are enabling the translation of these techniques out of the laboratory, and into the field. Here we examine the advances that are enabling portable liquid chromatography (LC). We explore the evolution of portable instrumentation from its inception to the most recent advances, highlighting the trends in the field and discussing the necessary criteria for developing in-field solutions. While instrumentation is becoming more capable it has yet to find adoption outside of research.
Issue Date: 15-Aug-2020
Date of Acceptance: 5-Aug-2020
URI: http://hdl.handle.net/10044/1/82206
DOI: 10.1007/s10337-020-03944-6
ISSN: 0009-5893
Publisher: Springer
Start Page: 1165
End Page: 1195
Journal / Book Title: Chromatographia
Volume: 83
Copyright Statement: © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Sponsor/Funder: Analytical Chemistry Trust Fund
Funder's Grant Number: 600322/02
Keywords: Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemical Research Methods
Chemistry, Analytical
Biochemistry & Molecular Biology
Chemistry
Portable HPLC
Miniaturised chromatography
Field chemistry
NONAQUEOUS CAPILLARY-ELECTROPHORESIS
SOLID-PHASE EXTRACTION
DRIED BLOOD SPOTS
MINIATURE MASS-SPECTROMETER
ESCHERICHIA-COLI O157H7
PROTECTED AMINO-ACIDS
ELECTROOSMOTIC-PUMP
HAND-HELD
ENANTIOMERIC SEPARATION
GRADIENT GENERATOR
Analytical Chemistry
0301 Analytical Chemistry
0399 Other Chemical Sciences
Publication Status: Published
Online Publication Date: 2020-08-15
Appears in Collections:Department of Surgery and Cancer
Electrical and Electronic Engineering
Faculty of Medicine
Faculty of Engineering



This item is licensed under a Creative Commons License Creative Commons