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Using non-invasive transcranial direct current stimulation for neglect and associated attentional deficits following stroke

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Title: Using non-invasive transcranial direct current stimulation for neglect and associated attentional deficits following stroke
Authors: Olgiati, E
Malhotra, P
Item Type: Journal Article
Abstract: Neglect is a disabling neuropsychological syndrome that is frequently observed following right-hemispheric stroke. Affected individuals often present with multiple attentional deficits, ranging from reduced orienting towards contralesional space to a generalized impairment in maintaining attention over time. Although a degree of spontaneous recovery occurs in most patients, in some individuals this condition can be treatment-resistant with prominent ongoing non-spatial deficits. Further, there is a large inter-individual variability in response to different therapeutic approaches. Given its potential to alter neuronal excitability and affect neuroplasticity, non-invasive brain stimulation is a promising tool that could potentially be utilized to facilitate recovery. However, there are many outstanding questions regarding its implementation in this heterogeneous patient group. Here we provide a critical overview of the available evidence on the use of non-invasive electrical brain stimulation, focussing on transcranial direct current stimulation (tDCS), to improve neglect and associated attentional deficits after right-hemispheric stroke. At present, there is insufficient robust evidence supporting the clinical use of tDCS to alleviate symptoms of neglect. Future research would benefit from careful study design, enhanced precision of electrical montages, multi-modal approaches exploring predictors of response, tailored dose-control applications and increased efforts to evaluate standalone tDCS versus its incorporation into combination therapy.
Issue Date: 1-May-2022
Date of Acceptance: 30-Jun-2020
URI: http://hdl.handle.net/10044/1/81235
DOI: 10.1080/09602011.2020.1805335
ISSN: 0960-2011
Publisher: Taylor & Francis (Routledge)
Start Page: 732
End Page: 763
Journal / Book Title: Neuropsychological Rehabilitation
Volume: 32
Issue: 5
Copyright Statement: © 2020 Taylor & Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in Neuropsychological Rehabilitation
Keywords: Science & Technology
Social Sciences
Life Sciences & Biomedicine
Neurosciences
Psychology
Neurosciences & Neurology
Neglect
tDCS
Attention
Vigilance
Stroke
UNILATERAL SPATIAL NEGLECT
THETA-BURST STIMULATION
POSTERIOR PARIETAL CORTEX
HUMAN MOTOR CORTEX
BRAIN-STIMULATION
PRISM ADAPTATION
VISUAL NEGLECT
WORKING-MEMORY
DOUBLE-BLIND
VISUOSPATIAL NEGLECT
Attention
Neglect
Stroke
Vigilance
tDCS
Brain
Humans
Neuronal Plasticity
Stroke
Stroke Rehabilitation
Transcranial Direct Current Stimulation
Brain
Humans
Neuronal Plasticity
Stroke
Transcranial Direct Current Stimulation
Stroke Rehabilitation
Rehabilitation
11 Medical and Health Sciences
17 Psychology and Cognitive Sciences
Publication Status: Published
Online Publication Date: 2020-09-07
Appears in Collections:Faculty of Medicine
Department of Brain Sciences