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Systematic review of combined functional near-infrared spectroscopy and transcranial direct-current stimulation studies.

Title: Systematic review of combined functional near-infrared spectroscopy and transcranial direct-current stimulation studies.
Authors: Patel, R
Dawidziuk, A
Darzi, A
Singh, H
Leff, DR
Item Type: Journal Article
Abstract: Significance: Combining transcranial direct-current stimulation (tDCS) with functional near-infrared spectroscopy (fNIRS) is a recent approach to exploring brain activation evoked by neurostimulation. Aim: To critically evaluate studies combining tDCS and fNIRS and provide a consolidated overview of cortical hemodynamic responses to neurostimulation. Approach: Key terms were searched in three databases (MEDLINE, EMBASE, and PsycINFO) with cross-referencing and works from Google Scholar also evaluated. All studies reporting on fNIRS-derived hemoglobin changes evoked by tDCS were included. Results: Literature searches revealed 474 articles, of which 28 were included for final review (22 in healthy individuals: 9 involving rest and 13 with tasks; 6 in the clinical setting). At rest, an overall increase in cortical activation was observed in fNIRS responses at the site of stimulation, with evidence suggesting nonstimulated brain regions are also similarly affected. Conversely, during tasks, reduced cortical activation was observed during online stimulation. Offline and poststimulation effects were less consistent, as is the impact on clinical populations and their symptom correlation. Conclusion: This review explores the methodological frameworks for fNIRS-tDCS evaluations and summarizes hemodynamic responses associated with tDCS in all populations. Our findings provide further evidence of the impact of tDCS on neuronal activation within functionally connected networks.
Issue Date: Apr-2020
Date of Acceptance: 15-Jun-2020
URI: http://hdl.handle.net/10044/1/81007
DOI: 10.1117/1.NPh.7.2.020901
ISSN: 2329-423X
Start Page: 020901
Journal / Book Title: Neurophotonics
Volume: 7
Issue: 2
Copyright Statement: © 2020 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Sponsor/Funder: National Institute of Health Research
Keywords: functional near-infrared spectroscopy
systematic review
transcranial direct-current stimulation
0903 Biomedical Engineering
1004 Medical Biotechnology
1109 Neurosciences
Publication Status: Published
Conference Place: United States
Appears in Collections:Department of Surgery and Cancer
Faculty of Medicine
Institute of Global Health Innovation