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Newly discovered Synechococcus sp. PCC 11901 is a robust cyanobacterial strain for high biomass production

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Title: Newly discovered Synechococcus sp. PCC 11901 is a robust cyanobacterial strain for high biomass production
Authors: Włodarczyk, A
Selão, TT
Norling, B
Nixon, PJ
Item Type: Journal Article
Abstract: Cyanobacteria, which use solar energy to convert carbon dioxide into biomass, are potential solar biorefineries for the sustainable production of chemicals and biofuels. However, yields obtained with current strains are still uncompetitive compared to existing heterotrophic production systems. Here we report the discovery and characterization of a new cyanobacterial strain, Synechococcus sp. PCC 11901, with promising features for green biotechnology. It is naturally transformable, has a short doubling time of ≈2 hours, grows at high light intensities and in a wide range of salinities and accumulates up to ≈33 g dry cell weight per litre when cultured in a shake-flask system using a modified growth medium − 1.7 to 3 times more than other strains tested under similar conditions. As a proof of principle, PCC 11901 engineered to produce free fatty acids yielded over 6 mM (1.5 g L−1), an amount comparable to that achieved by similarly engineered heterotrophic organisms.
Issue Date: 7-May-2020
Date of Acceptance: 16-Mar-2020
URI: http://hdl.handle.net/10044/1/78944
DOI: 10.1038/s42003-020-0910-8
ISSN: 2399-3642
Publisher: Nature Research (part of Springer Nature)
Journal / Book Title: Communications Biology
Volume: 3
Copyright Statement: © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Publication Status: Published
Article Number: ARTN 215
Appears in Collections:Faculty of Natural Sciences