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Report 19: The potential impact of the COVID-19 epidemic on HIV, TB and malaria in low- and middle-income countries

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Title: Report 19: The potential impact of the COVID-19 epidemic on HIV, TB and malaria in low- and middle-income countries
Authors: Hogan, A
Jewell, B
Sherrard-Smith, E
Vesga, J
Watson, O
Whittaker, C
Hamlet, A
Smith, J
Ainslie, K
Baguelin, M
Bhatt, S
Boonyasiri, A
Brazeau, N
Cattarino, L
Charles, G
Cooper, L
Coupland, H
Cuomo-Dannenburg, G
Dighe, A
Djaafara, A
Donnelly, C
Dorigatti, I
Eaton, J
Van Elsland, S
Fitzjohn, R
Fu, H
Gaythorpe, K
Green, W
Haw, D
Hayes, S
Hinsley, W
Imai, N
Knock, E
Laydon, D
Lees, J
Mangal, T
Mellan, T
Mishra, S
Nedjati Gilani, G
Nouvellet, P
Okell, L
Ower, A
Parag, K
Pickles, M
Stopard, I
Thompson, H
Unwin, H
Verity, R
Vollmer, M
Walters, C
Wang, H
Wang, Y
Whittles, L
Winskill, P
Xi, X
Ferguson, N
Churcher, T
Arinaminpathy, N
Ghani, A
Walker, P
Hallett, T
Item Type: Report
Abstract: COVID-19 has the potential to cause disruptions to health services in different ways; through the health system becoming overwhelmed with COVID-19 patients, through the intervention used to slow transmission of COVID-19 inhibiting access to preventative interventions and services, and through supplies of medicine being interrupted. We aim to quantify the extent to which such disruptions in services for HIV, TB and malaria in high burden low- and middle-income countries could lead to additional loss of life. In high burden settings, HIV, TB and malaria related deaths over 5 years may be increased by up to 10%, 20% and 36%, respectively, compared to if there were no COVID-19 epidemic. We estimate the greatest impact on HIV to be from interruption to ART, which may occur during a period of high or extremely high health system demand; for TB, we estimate the greatest impact is from reductions in timely diagnosis and treatment of new cases, which may result from a long period of COVID-19 suppression interventions; for malaria, we estimate that the greatest impact could come from reduced prevention activities including interruption of planned net campaigns, through all phases of the COVID-19 epidemic. In high burden settings, the impact of each type of disruption could be significant and lead to a loss of life-years over five years that is of the same order of magnitude as the direct impact from COVID-19 in places with a high burden of malaria and large HIV/TB epidemics. Maintaining the most critical prevention activities and healthcare services for HIV, TB and malaria could significantly reduce the overall impact of the COVID-19 epidemic.
Issue Date: 1-May-2020
URI: http://hdl.handle.net/10044/1/78670
DOI: https://doi.org/10.25561/78670
Start Page: 1
End Page: 29
Copyright Statement: © 2020 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: MR/R015600/1
Publication Status: Published
Appears in Collections:Imperial College London COVID-19
School of Public Health