1
IRUS Total
Downloads

The "broken escalator" phenomenon: vestibular dizziness interferes with locomotor adaptation

File Description SizeFormat 
LocomotorAdaptation_VN_MD_JVR_Accepted.docxAccepted version728.11 kBMicrosoft WordView/Open
Title: The "broken escalator" phenomenon: vestibular dizziness interferes with locomotor adaptation
Authors: Patel, M
Roberts, E
Arshad, Q
Bunday, K
Golding, JF
Kaski, D
Bronstein, AM
Item Type: Journal Article
Abstract: BACKGROUND: Although vestibular lesions degrade postural control we do not know the relative contributions of the magnitude of the vestibular loss and subjective vestibular symptoms to locomotor adaptation. OBJECTIVE: To study how dizzy symptoms interfere with adaptive locomotor learning. METHODS: We examined patients with contrasting peripheral vestibular deficits, vestibular neuritis in the chronic stable phase (n = 20) and strongly symptomatic unilateral Meniere's disease (n = 15), compared to age-matched healthy controls (n = 15). We measured locomotor adaptive learning using the "broken escalator" aftereffect, simulated on a motorised moving sled. RESULTS: Patients with Meniere's disease had an enhanced "broken escalator" postural aftereffect. More generally, the size of the locomotor aftereffect was related to how symptomatic patients were across both groups. Contrastingly, the degree of peripheral vestibular loss was not correlated with symptom load or locomotor aftereffect size. During the MOVING trials, both patient groups had larger levels of instability (trunk sway) and reduced adaptation than normal controls. CONCLUSION: Dizziness symptoms influence locomotor adaptation and its subsequent expression through motor aftereffects. Given that the unsteadiness experienced during the "broken escalator" paradigm is internally driven, the enhanced aftereffect found represents a new type of self-generated postural challenge for vestibular/unsteady patients.
Issue Date: 1-May-2020
Date of Acceptance: 24-Jan-2020
URI: http://hdl.handle.net/10044/1/77834
DOI: 10.3233/VES-200693
ISSN: 0957-4271
Publisher: IOS Press
Start Page: 81
End Page: 94
Journal / Book Title: Journal of Vestibular Research: Equilibrium and Orientation: an international journal of experimental and clinical vestibular science
Volume: 30
Issue: 2
Copyright Statement: ©2020 IOS Press All rights reserved.
Keywords: Meniere’s disease
Vestibular system
dizziness
locomotor adaptation
motor control
vertigo
vestibular neuritis
Meniere’s disease
Vestibular system
dizziness
locomotor adaptation
motor control
vertigo
vestibular neuritis
Neurology & Neurosurgery
1116 Medical Physiology
Publication Status: Published
Conference Place: Netherlands
Online Publication Date: 2020-02-26
Appears in Collections:Faculty of Medicine
Department of Brain Sciences



Unless otherwise indicated, items in Spiral are protected by copyright and are licensed under a Creative Commons Attribution NonCommercial NoDerivatives License.

Creative Commons