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Mother-to-child transmission of hepatitis B: What more needs to be done to eliminate it around the world?

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Title: Mother-to-child transmission of hepatitis B: What more needs to be done to eliminate it around the world?
Authors: Nayagam, S
Shimakawa, Y
Lemoine, M
Item Type: Journal Article
Abstract: Mother‐to‐child transmission (MTCT) of hepatitis B virus (HBV) is a key component of the hepatitis B burden worldwide. Despite its efficacy to prevent HBV transmission, infant vaccination is not enough to control HBV MTCT. Additional efforts are urgently needed to evaluate and scale‐up preventive strategies especially in endemic countries, which are most affected. This review highlights the efficacy and barriers of the currently validated measures for the prevention of HBV MTCT and proposes alternatives adapted to resource‐limited settings to eventually achieve HBV elimination worldwide.
Issue Date: Apr-2020
Date of Acceptance: 12-Aug-2019
URI: http://hdl.handle.net/10044/1/76856
DOI: 10.1111/jvh.13231
ISSN: 1345-2533
Publisher: Wiley
Start Page: 342
End Page: 349
Journal / Book Title: Journal of Viral Hepatitis
Volume: 27
Issue: 4
Copyright Statement: © 2019 John Wiley & Sons Ltd. This is the accepted version of the following article: Nayagam, S, Shimakawa, Y, Lemoine, M. Mother‐to‐child transmission of hepatitis B: What more needs to be done to eliminate it around the world? J Viral Hepat. 2019; 00: 1– 8, which has been published in final form at https://doi.org/10.1111/jvh.13231
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: MR/R015600/1
Keywords: Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
Infectious Diseases
Virology
elimination
HBV
mother-to-child transmission
prevention
vaccine
COST-EFFECTIVENESS ANALYSIS
PREVENT PERINATAL TRANSMISSION
TENOFOVIR DISOPROXIL FUMARATE
CONTROLLED TEMPERATURE CHAIN
SINGLE-USE INJECTION
VIRUS INFECTION
E-ANTIGEN
VERTICAL TRANSMISSION
INFANT TRANSMISSION
ECONOMIC-EVALUATION
HBV
elimination
mother-to-child transmission
prevention
vaccine
Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
Infectious Diseases
Virology
elimination
HBV
mother-to-child transmission
prevention
vaccine
COST-EFFECTIVENESS ANALYSIS
PREVENT PERINATAL TRANSMISSION
TENOFOVIR DISOPROXIL FUMARATE
CONTROLLED TEMPERATURE CHAIN
SINGLE-USE INJECTION
VIRUS INFECTION
E-ANTIGEN
VERTICAL TRANSMISSION
INFANT TRANSMISSION
ECONOMIC-EVALUATION
0605 Microbiology
1103 Clinical Sciences
1108 Medical Microbiology
Gastroenterology & Hepatology
Publication Status: Published online
Online Publication Date: 2019-11-07
Appears in Collections:School of Public Health