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Statistical shape modelling of the first carpometacarpal joint reveals high variation in morphology

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Title: Statistical shape modelling of the first carpometacarpal joint reveals high variation in morphology
Authors: Rusli, W
Kedgley, A
Item Type: Journal Article
Abstract: The first carpometacarpal (CMC) joint, located at the base of the thumb and formed by the junction between the first metacarpal and trapezium, is a common site for osteoarthritis of the hand. The shape of both the first metacarpal and trapezium contributes to the intrinsic bony stability of the jointandvariability in the morphology of both these bones can affect the joint’s function. The objectivesof this study wereto quantify the morphological variation of the complete metacarpal and trapeziumand determine anycorrelation between anatomical features ofthese two components of the first CMC joint. A multi-object statistical shape modelling pipeline, consisting of scaling, hierarchical rigid registration, non-rigid registration and projection pursuit principal component analysis, was implemented. Four anatomical measureswere quantified from the shape model, namely the first metacarpal articular tilt and torsion angles and the trapeziumlength and width.Variationsin the first metacarpal articulartilt angle (-6.3°<θ<12.3°) and trapezium width (10.28mm <𝓌<11.13mm)wereidentified in the firstprincipal component. In the second principal component, variationsin the first metacarpal14torsion angle (0.2°<α<14.2°), first metacarpal articular tilt angle (1.0°<θ<6.4°) and trapezium length (12.25mm <ℓ<17.33mm)weredetermined. Due to their implications for joint stability, the first metacarpal articular tilt angle and trapezium width maybe important anatomical features which couldbe used toadvance early detectionand treatment offirst CMC joint osteoarthritis.
Issue Date: 1-Aug-2020
Date of Acceptance: 16-Oct-2019
URI: http://hdl.handle.net/10044/1/74669
DOI: 10.1007/s10237-019-01257-8
ISSN: 1617-7940
Publisher: Springer (part of Springer Nature)
Start Page: 1203
End Page: 1210
Journal / Book Title: Biomechanics and Modeling in Mechanobiology
Volume: 19
Copyright Statement: © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: Science & Technology
Life Sciences & Biomedicine
Technology
Biophysics
Engineering, Biomedical
Engineering
Statistical shape modelling
First carpometacarpal joint
Morphology
Articular tilt angle
First metacarpal torsion angle
THUMB
OSTEOARTHRITIS
WOMEN
MEN
REGISTRATION
STABILITY
TORSION
HUMANS
WRIST
TILT
Articular tilt angle
First carpometacarpal joint
First metacarpal torsion angle
Morphology
Statistical shape modelling
0903 Biomedical Engineering
0913 Mechanical Engineering
Biomedical Engineering
Publication Status: Published
Online Publication Date: 2019-11-21
Appears in Collections:Bioengineering
Faculty of Engineering



This item is licensed under a Creative Commons License Creative Commons