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Secondary analysis of electronic health records

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Title: Secondary analysis of electronic health records
Authors: MIT Critical Data
Komorowski, M
Item Type: Book
Abstract: This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.
Editors: Komorowski, M
Issue Date: 31-Dec-2016
URI: http://hdl.handle.net/10044/1/73577
DOI: https://dx.doi.org/10.1007/978-3-319-43742-2
ISBN: 978-3-319-82899-2
Publisher: Springer International Publishing
Start Page: 1
End Page: 427
Copyright Statement: © The Editor(s) (if applicable) and The Author(s) 2016 This book is published open access.Open AccessThis book is distributed under the terms of the Creative CommonsAttribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/),which permits any noncommercial use, duplication, adaptation, distribution and reproduction in anymedium or format, as long as you give appropriate credit to the original author(s) and the source, a link isprovided to the Creative Commons license and any changes made are indicated.The images or other third party material in this book are included in the work’s Creative Commonslicense, unless indicated otherwise in the credit line; if such material is not included in the work’sCreative Commons license and the respective action is not permitted by statutory regulation, users willneed to obtain permission from the license holder to duplicate, adapt or reproduce the material.The use of general descriptive names, registered names, trademarks, service marks, etc. in this publi-cation does not imply, even in the absence of a specific statement, that such names are exempt from therelevant protective laws and regulations and therefore free for general use.The publisher, the authors and the editors are safe to assume that the advice and information in thisbook are believed to be true and accurate at the date of publication. Neither the publisher nor theauthors or the editors give a warranty, express or implied, with respect to the material contained herein orfor any errors or omissions that may have been made.
Sponsor/Funder: Engineering and Physical Sciences Research Council (EPSRC) & alumni
Publication Status: Published
Open Access location: https://www.springer.com/gp/book/9783319437408#aboutBook
Online Publication Date: 2016-09-01
Appears in Collections:Department of Surgery and Cancer