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Protocol for the OUTREACH trial: A randomised trial comparing delivery of cancer systemic therapy in three different settings - patient's home, GP surgery and hospital day unit

Title: Protocol for the OUTREACH trial: A randomised trial comparing delivery of cancer systemic therapy in three different settings - patient's home, GP surgery and hospital day unit
Authors: Corrie, PG
Moody, M
Wood, V
Bavister, L
Prevost, T
Parker, RA
Sabes-Figuera, R
McCrone, P
Balsdon, H
McKinnon, K
O'Sullivan, B
Tan, RS
Barclay, SIG
Item Type: Journal Article
Abstract: Background The national Cancer Reform Strategy recommends delivering care closer to home whenever possible. Cancer drug treatment has traditionally been administered to patients in specialist hospital-based facilities. Technological developments mean that nowadays, most treatment can be delivered in the out-patient setting. Increasing demand, care quality improvements and patient choice have stimulated interest in delivering some treatment to patients in the community, however, formal evaluation of delivering cancer treatment in different community settings is lacking. This randomised trial compares delivery of cancer treatment in the hospital with delivery in two different community settings: the patient's home and general practice (GP) surgeries. Methods/design Patients due to receive a minimum 12 week course of standard intravenous cancer treatment at two hospitals in the Anglia Cancer Network are randomised on a 1:1:1 basis to receive treatment in the hospital day unit (control arm), or their own home, or their choice of one of three neighbouring GP surgeries. Overall patient care, treatment prescribing and clinical review is undertaken according to standard local practice. All treatment is dispensed by the local hospital pharmacy and treatment is delivered by the hospital chemotherapy nurses. At four time points during the 12 week study period, information is collected from patients, nursing staff, primary and secondary care teams to address the primary end point, patient-perceived benefits (using the emotional function domain of the EORTC QLQC30 patient questionnaire), as well as secondary end points: patient satisfaction, safety and health economics. Discussion The Outreach trial is the first randomised controlled trial conducted which compares delivery of out-patient based intravenous cancer treatment in two different community settings with standard hospital based treatment. Results of this study may better inform all key stakeholders regarding potential costs and benefits of transferring clinical services from hospital to the community. Trial registration number ISRCTN: ISRCTN66219681
Issue Date: 29-Oct-2011
Date of Acceptance: 29-Oct-2011
URI: http://hdl.handle.net/10044/1/71992
DOI: https://dx.doi.org/10.1186/1471-2407-11-467
ISSN: 1471-2407
Publisher: BioMed Central
Journal / Book Title: BMC Cancer
Volume: 11
Copyright Statement: © 2011 Corrie et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: NIHR Research for Patient Benefit
Funder's Grant Number: PB-PG-0107-12101
Keywords: Science & Technology
Life Sciences & Biomedicine
Oncology
cancer treatment
chemotherapy
community care
care closer to home
out-patient service delivery
COST-ANALYSIS
CHEMOTHERAPY
PREFERENCES
SAFETY
Adult
Aged
Antineoplastic Agents
Community Health Centers
Day Care, Medical
Delivery of Health Care
Family Practice
Female
Home Care Services
Humans
Injections, Intravenous
Male
Middle Aged
Neoplasms
Patient Satisfaction
Prospective Studies
Quality of Life
Young Adult
Humans
Neoplasms
Antineoplastic Agents
Day Care
Injections, Intravenous
Prospective Studies
Family Practice
Quality of Life
Adult
Aged
Middle Aged
Community Health Centers
Home Care Services
Patient Satisfaction
Delivery of Health Care
Female
Male
Young Adult
Science & Technology
Life Sciences & Biomedicine
Oncology
cancer treatment
chemotherapy
community care
care closer to home
out-patient service delivery
COST-ANALYSIS
CHEMOTHERAPY
PREFERENCES
SAFETY
1112 Oncology and Carcinogenesis
Oncology & Carcinogenesis
Publication Status: Published
Article Number: 467
Appears in Collections:School of Public Health