79
IRUS TotalDownloads
Altmetric
ASKing no more: the emerging role of DUSP12 in the regulation of hepatic lipid metabolism
| File | Description | Size | Format | |
|---|---|---|---|---|
 HEP-19-0840-R1_Manuscript.pdf | Accepted version | 4.29 MB | Adobe PDF | View/Open |
| Title: | ASKing no more: the emerging role of DUSP12 in the regulation of hepatic lipid metabolism |
| Authors: | Bubici, C Lepore, A Papa, S |
| Item Type: | Journal Article |
| Abstract: | Accumulation of fat in liver cells not due to alcohol abuse is the hallmark of non-alcoholic fatty liver disease (NAFLD), a common condition that may progress to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation.(1) Over a long period of time, NASH may lead to fibrosis with consequent cirrhosis, which in turn predisposes patients to hepatocellular carcinoma. |
| Issue Date: | 1-Oct-2019 |
| Date of Acceptance: | 7-Jul-2019 |
| URI: | http://hdl.handle.net/10044/1/71632 |
| DOI: | 10.1002/hep.30851 |
| ISSN: | 0270-9139 |
| Publisher: | Wiley |
| Start Page: | 1091 |
| End Page: | 1094 |
| Journal / Book Title: | Hepatology |
| Volume: | 70 |
| Issue: | 4 |
| Copyright Statement: | © 2019 Owner. This is the accepted version of the following article: Bubici, C. , Lepore, A. and Papa, S. (2019), ASKing no more: the emerging role of DUSP12 in the regulation of hepatic lipid metabolism. Hepatology. Accepted Author Manuscript. doi:10.1002/hep.30851, which has been published in final form at https://doi.org/10.1002/hep.30851. |
| Keywords: | Science & Technology Life Sciences & Biomedicine Gastroenterology & Hepatology ASK1 ASK1 hepatic lipid metabolism mitogen-activated protein kinase nonalcoholic fatty liver disease Gastroenterology & Hepatology 1103 Clinical Sciences 1101 Medical Biochemistry and Metabolomics |
| Publication Status: | Published |
| Conference Place: | United States |
| Online Publication Date: | 2019-07-12 |
| Appears in Collections: | Department of Metabolism, Digestion and Reproduction |