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Subject-specific modelling of pneumoperitoneum: model implementation, validation and human feasibility assessment

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Title: Subject-specific modelling of pneumoperitoneum: model implementation, validation and human feasibility assessment
Authors: Camara, M
Dawda, S
Mayer, E
Darzi, A
Pratt, P
Item Type: Journal Article
Abstract: PURPOSE: The aim of this study is to propose a model that simulates patient-specific anatomical changes resulting from pneumoperitoneum, using preoperative data as input. The framework can assist the surgeon through a real-time visualisation and interaction with the model. Such could further facilitate surgical planning preoperatively, by defining a surgical strategy, and intraoperatively to estimate port positions. METHODS: The biomechanical model that simulates pneumoperitoneum was implemented within the GPU-accelerated NVIDIA FleX position-based dynamics framework. Datasets of multiple porcine subjects before and after abdominal insufflation were used to generate, calibrate and validate the model. The feasibility of modelling pneumoperitoneum in human subjects was assessed by comparing distances between specific landmarks from a patient abdominal wall, to the same landmark measurements on the simulated model. RESULTS: The calibration of simulation parameters resulted in a successful estimation of an optimal set parameters. A correspondence between the simulation pressure parameter and the experimental insufflation pressure was determined. The simulation of pneumoperitoneum in a porcine subject resulted in a mean Hausdorff distance error of 5-6 mm. Feasibility of modelling pneumoperitoneum in humans was successfully demonstrated. CONCLUSION: Simulation of pneumoperitoneum provides an accurate subject-specific 3D model of the inflated abdomen, which is a more realistic representation of the intraoperative scenario when compared to preoperative imaging alone. The simulation results in a stable and interactive framework that performs in real time, and supports patient-specific data, which can assist in surgical planning.
Issue Date: 1-May-2019
Date of Acceptance: 8-Feb-2019
URI: http://hdl.handle.net/10044/1/67936
DOI: https://dx.doi.org/10.1007/s11548-019-01924-2
ISSN: 1861-6429
Publisher: Springer Verlag
Start Page: 841
End Page: 850
Journal / Book Title: International Journal of Computer Assisted Radiology and Surgery
Volume: 14
Issue: 5
Copyright Statement: © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Sponsor/Funder: Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust
National Institute of Health Research
Funder's Grant Number: RDB04 79560
RD207
RDB04
RDB04
UR150
Keywords: Science & Technology
Technology
Life Sciences & Biomedicine
Engineering, Biomedical
Radiology, Nuclear Medicine & Medical Imaging
Surgery
Engineering
Pneumoperitoneum
Surgical planning
Biomechanical modelling
Position-based dynamics
DEFORMATION
Biomechanical modelling
Pneumoperitoneum
Position-based dynamics
Surgical planning
Abdominal Wall
Animals
Feasibility Studies
Humans
Imaging, Three-Dimensional
Insufflation
Laparoscopy
Models, Biological
Pneumoperitoneum, Artificial
Pressure
Swine
Tomography, X-Ray Computed
Abdominal Wall
Animals
Swine
Humans
Tomography, X-Ray Computed
Imaging, Three-Dimensional
Laparoscopy
Pneumoperitoneum, Artificial
Insufflation
Feasibility Studies
Pressure
Models, Biological
Biomechanical modelling
Pneumoperitoneum
Position-based dynamics
Surgical planning
Nuclear Medicine & Medical Imaging
1103 Clinical Sciences
Publication Status: Published
Conference Place: Germany
Online Publication Date: 2019-02-20
Appears in Collections:Department of Surgery and Cancer
Institute of Global Health Innovation