The type VI secretion system: a tubular story

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Title: The type VI secretion system: a tubular story
Authors: Filloux, A
Item Type: Journal Article
Abstract: The molecular mechanism by which proteins are secreted in gram‐negative bacteria is supported by nanomachines called type I to type VI secretion systems (T1SS to T6SS). Previous data suggested that the ClpV ATPase energizes the transport of Hcp and VgrG proteins through the T6SS secretion channel. The identification of a yet unknown tubular structure, which interacts with ClpV, adds another level of complexity and challenges our vision of the T6SS working model.
Issue Date: 18-Feb-2009
Date of Acceptance: 1-Feb-2009
ISSN: 0261-4189
Publisher: EMBO Press
Start Page: 309
End Page: 310
Journal / Book Title: EMBO Journal
Volume: 28
Issue: 4
Copyright Statement: © 2009 European Molecular Biology Organization. This article is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Licence. []
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: G0800171
Keywords: Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Cell Biology
Adenosine Triphosphatases
Bacterial Proteins
Biological Transport
Cell Membrane
Gene Expression Regulation, Bacterial
Genes, Bacterial
Gram-Negative Bacteria
Models, Biological
Protein Transport
Virulence Factors
06 Biological Sciences
08 Information And Computing Sciences
11 Medical And Health Sciences
Developmental Biology
Publication Status: Published
Online Publication Date: 2009-02-18
Appears in Collections:Faculty of Natural Sciences

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