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Impairments of attention in Alzheimer’s disease

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Title: Impairments of attention in Alzheimer’s disease
Authors: Malhotra, P
Item Type: Journal Article
Abstract: Alzheimer’s Disease (AD) is characteristically perceived as primarily being a disorder of episodic memory, with prominent attentional impairments more typically being associated with other neurodegenerative conditions, such as Dementia with Lewy Bodies. However, attention is also affected early on in Alzheimer’s, particularly in individuals with young onset and atypical syndromes. In addition, some initial symptoms that are apparently due to episodic memory loss may be secondary to failures of attentional processes. This review describes the various attentional impairments that can be observed in patients with AD, and addresses them through the conceptual framework of attention proposed by Posner and Petersen. It also explains how current knowledge of the development of AD has influenced our understanding of how these deficits arise. Finally, there is a brief summary of the effects of current AD treatments on attentional deficits, and how future pharmacological approaches might better target these deficits.
Issue Date: 1-Oct-2019
Date of Acceptance: 1-Nov-2018
URI: http://hdl.handle.net/10044/1/64328
DOI: https://dx.doi.org/10.1016/j.copsyc.2018.11.002
ISSN: 2352-250X
Publisher: Elsevier BV
Start Page: 41
End Page: 48
Journal / Book Title: Current Opinion in Psychology
Volume: 29
Copyright Statement: © 2018 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
Publication Status: Published
Online Publication Date: 2018-11-08
Appears in Collections:Department of Medicine (up to 2019)