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Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study
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 Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.pdf | Published version | 894.53 kB | Adobe PDF | View/Open |
| Title: | Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study |
| Authors: | Drake, TM Camilleri-Brennan, J Tabiri, S Fergusson, SJ Spence, R Fitzgerald, JEF Bhangu, A Harrison, EM Ademuyiwa, AO Fergusson, S Glasbey, JC Khatri, C Mohan, M Nepogodiev, D Soreide, K Gobin, N Freitas, AV Hall, N Kim, S-H Negida, A Jaffry, Z Chapman, SJ Arnaud, AP Recinos, G Manipal, CE Amandito, R Shawki, M Hanrahan, M Pata, F Zilinskas, J Roslani, AC Goh, CC Irwin, G Shu, S Luque, L Shiwani, H Altamimi, A Alsaggaf, MU Rayne, S Jeyakumar, J Cengiz, Y Raptis, DA Fermani, C Balmaceda, R Marta Modolo, M Macdermid, E Chenn, R Yong, CO Edye, M Jarmin, M D'amours, SK Iyer, D Youssef, D Phillips, N Brown, J George, R Koh, C Warren, O Hanley, I Dickfos, M Nawara, C Oefner, D Primavesi, F Mitul, AR Mahmud, K Hussain, M Hakim, H Kumar, T Oosterkamp, A Assouto, PA Lawani, I Souaibou, YI Tun, AK Chong, CL Devadasar, GH Qadir, MRM Aung, KP Yeo, LS Palomino Castillo, VD Munhoz, MM Moreira, G Barros De Castro Segundo, LC Khouri Ferreira, SA Careta, MC Kim, SB De Sousa, AV Lazzarini Cury, AD Soares Miguel, GP Carreiro De Freitas, AV Silvestre, BP Pinto Vianna, JG Felipe, CO Valente Laufer, LA Altoe, F Da Silva, LA Pimenta, ML Giuriato, TF Bezerra Morais, PA Luiz, JS Araujo, R Menegussi, J Leal, M Barroso de Lima, CV Tatagiba, LS Leal, A Dos Santos, DV Fraga, GP Simoes, RL Stock, S Nigo, S Kabba, J Ngwa, TE Brown, J King, S Zani, A Azzie, G Firdouse, M Kushwaha, S Agarwal, A Bailey, K Cameron, B Livingston, M Horobjowsky, A Deckelbaum, DL Razek, T Marinkovic, B Grasset, E D'aguzan, N Jimenez, J Macchiavello, R Zhang, Z Guo, W Oh, J Zheng, F Montes, I Sierra, S Mendez, M Isabel Villegas, M Mendoza Arango, MC Mendoza, I Naranjo Aristizabal, FA Montoya Botero, JA Quintero Riaza, VM Restrepo, J Morales, C Cruz, H Munera, A Karlo, R Domini, E Mihanovic, J Radic, M Zamarin, K Pezelj, N Hache-Marliere, M Batista Lemaire, S Rivas, R Khyrallh, A Hassan, A Shimy, G Fahmy, MAB Nabawi, A Elfil, M Ghoneem, M Gohar, ME-SAM Asal, M Abdelkader, M Gomah, M Rashwan, H Karkeet, M Gomaa, A Hasan, A Elgebaly, A Saleh, O Fattah, AA Gouda, A Elshafay, AE Gharib, A Menshawy, A Hanafy, M Al-Mallah, A Abdulgawad, M Baheeg, M Alhendy, M AbdelFattah, I Kenibar, A Osman, O Gemeah, M Mohammed, A Adel, A Mohammed, A Sayed, A Abozaid, M Kotb, AHE-B Ata, AAA Nasr, M Alkammash, A Saeed, M Abd El Hamid, N Attia, AM Abd El Galeel, A Elbanby, E El-Dien, KS Hantour, U Alahmady, O Mansour, B Elkorashy, AM Taha, EMS Lasheen, KT Elkolaly, SS Abdel-Wahab, NYE Abozyed, MAF Adel, A Saeed, AM El Sayed, GS Youssif, JH Ahmed, SM El-Shahat, NS Khedr, AE-RH Elsebaaye, AO Elzayat, M Abdelraheim, M Elzayat, I Warda, M El Deen, KN Elnemr, AE Salah, O Abbas, M Rashad, M Elzayyat, I Hemeda, D Tawfik, G Salama, M Khaled, H Seisa, M Elshaer, K Hussein, A Elkhadrawi, M Afifi, AM Ebrahim, OS Metwally, MM Elmelegy, R Elsawahly, DME Safa, H Nofal, E Elbermawy, M Ghazy, AA Samih, H Abdelgelil, A Abdelghany, S El Kholy, A Aboraya, M Elkady, F Salma, M Samy, S Fakher, R Aboarab, A Samir, A Sakr, A Haroun, A Al-Aarag, AA-R Elkholy, A Elshanwany, S Ghanem, E Tammam, A Hammad, AM El Shoura, Y El Ashal, G Khairy, H Antar, S Mehrez, S Abdelshafy, M Hamad, MGM Hosh, M Abdallah, E Magdy, B Alzayat, T Gamaly, E Elfeki, H Abouzahra, A Elsheikh, S Elgendy, FI Abd El-Salam, F Seifelnasr, O Ammar, M Eysa, A Sadek, A Toeema, AG Nasr, A Abuseif, M Zidan, H Barakat, SAE Elsayed, N Abd Elrasoul, Y Elkelany, A Ammar, MS Mustafa, M-A Hegazy, Y Etman, M Saad, S Alrahawy, M Raslan, A Morsi, M Rslan, A Sabry, A Elwakil, H Shaker, H Abd-Elrasoul, Y El-Kashef, H Shaalan, M Tarek, A Elwan, A Nayel, AR Seif, M Emadeldin, D Ghonaim, MA Almallah, A Fouad, A Sayma, EA Elbatahgy, A El-Ma'doul, AS Mosad, A Tolba, H Elsorogy, DEAA Mostafa, HA Omar, AA Abd El Hameed, OS Lasheen, A Abd El Salam, Y Morsi, A Ismail, M El-badawy, HA Amer, MA El-Hamouly, AS Attallah, NA Mosalum, O Afandy, A Mokhtar, A Abouelnasr, A Ayad, S Shaker, R Sakr, R Shaker, R Amreia, M Elsobky, S Mustafa, M El Magd, AA Marey, A Hafez, AT Zalabia, MF Mohamed, MM Fadel, A Ahmed, EA Ali, A Alwafai, MG Dwydar, A Kharsa, S Mamdouh, E El-Sheemy, H AlYoussef, I Aly, AK Aldalaq, A Alnawam, E Alkhabbaz, D Saad, M Hussein, S Elazayem, AA Meshref, A Elashmawy, M Mousa, M Nashaat, A Ghanem, S Elsayed, ZM Elwaey, A Elkadsh, I Darweesh, M Mohameden, A Hafez, M Badr, A Badwy, A Abd El Slam, M Elazoul, M Al-Nahrawi, S Eldamaty, L Nada, F Ameen, M Hagar, A Elsehimy, M Aboraya, M Dawoud, H El Mesery, S El Gendy, A Abdelkareem, A Marey, AS Allam, M Shehata, S Abozeid, K Elshobary, M Fahiem, A Sarsik, S Hashish, A Zidan, M Hashish, M Aql, S Elhendawy, AOA Husseini, M Kasem, E Gheith, A Elfouly, Y Soliman, AR Ibrahim, Y Elfouly, N Fawzy, A Hassan, A Rashid, M Elsherbiny, AS Sieda, B Badwi, NM Mohammed, MMH Mohamed, O Habeeb, MA Worku, M Starr, N Desta, S Wondimu, S Abebe, NS Thomas, E Asele, FA Dabessa, D Abebe, NS Zerihun, AB Mentula, P Leppaniemi, A Sallinen, V Scalabre, A Frade, F Irtan, S Graffeille, V Gaignard, E Alimi, Q Graffieille, V Abbo, O Mouttalib, S Bouali, O Hervieux, E Aigrain, Y Botto, N Faure, A Fievet, L Panait, N Eyssartier, E Schmitt, F Podevin, G Parent, V Martin, A Arnaud, AP Muller, C Bonnard, A Peycelon, M Abantanga, F Boakye-Yiadom, K Bukari, M Owusu, F Awuku-Asabre, J Bray, LD Lytras, D Psarianos, K Bamicha, A Kefalidi, E Gemenetzis, G Dervenis, C Gouvas, N Agalianos, C Kontos, M Kouraklis, G Karousos, D Germanos, S Marinos, C Anthoulakis, C Nikoloudis, N Mitroudis, N Estupinian, S Forno, W Arevalo Azmitia, JR Ramarez Cabrera, CC Guevara, R Aguilera, M Mendez, N Azmitia Mendizabal, CA Ramazzini, P Contreras Urquizu, M Tale, F Soley, R Barrios, E Barrios, E Marroquin Rodriguez, DE Perez Velasquez, CI Contreras Merida, SM Regalado, F Lopez, M Siguantay, M Lam, FY Szeto, KJ-Y Szeto, CCL Li, WS Li, KKK Leung, MF Mak, T Ng, S Prasad, SS Kirishnan, A Gyanchandani, N Kumar, BS Rangarajan, M Bhat, S Sreedharan, A Kinnera, SV Reddy, Y Venugopal, C Kumar, S Mittal, A Nadkarni, S Lakshmi, HN Malik, P Limaye, N Pai, S Jain, P Khajanchi, M Satoskar, S Satoskar, R Bin Mahamood, A Sutanto, EPR Soeselo, DA Tedjaatmadja, C Rahmawati, FN Mayasari, M Al-Hasani, RKMJ Al-Hameedi, HII Ibraheem, HI Al-Azraqi, IAA Sabeeh, L Kamil, R Telfah, MM Rasendran, A Sheehan, J Kerley, R Normile, C Gilbert, RW Song, J Dablouk, M Mauro, L Dablouk, MO Kielty, P Marks, E Gosling, S Mccarthy, M Mirghani, D Naqvi, SA Wong, CS Chung, S D'cruz, R Cahill, R Gosling, SG Fahy, C Cadogan, DD Powell, A Gilbert, R Clifford, C Driscoll, A Paul, S Lee, C Bowe, R Hutch, W Mohan, H O'neill, M Mealy, K Danelli, P Bondurri, A Maffioli, A Pasini, M Pata, G Roncali, S Silvani, P Carlucci, M Faccincani, R Bonavina, L Macchitella, Y Ceriani, C Tugnoli, G Di Saverio, S Khattab, K Paludi, MA Pata, D Cloro, LM Allegri, A Ansaloni, L Coccolini, F Veronese, E Bortolasi, L Hasheminia, A Nastri, G Dal Canto, M Cucumazzo, S Benevento, A Tessera, G Grandinetti, PP Maniscalco, A Lamanna, GL Turati, L Sgroi, G Rausa, E Villa, R Monteleone, M Merlini, D Grassi, V Cirocchi, R Cacurri, A Waleed, H Diab, A Elzowawi, F Jokubauskas, M Varkalys, K Venskutonis, D Pranevicius, R Ambrozeviciute, V Juciute, S Skardziukaite, A Bradulskis, S Urbanavicius, L Austraite, A Riauka, R Dambrauskas, Z Karumnas, P Urniezius, Z Zilinskiene, R Rudzenskaite, A Usaityte, A Montrimaite, M Kaselis, N Strazdas, A Jokubonis, K Maceviciute, K Beisa, V Poskus, T Strupas, K Laugzemys, E Kolosov, A Jotautas, V Rakita, I Mikalauskas, S Kazanavicius, D Rackauskas, R Rakauskas, R Preckailaite, E Coomber, R Johnson, K Nowers, J Periasammy, D Salleh, A Das, A Tze, RGE Kumar, MN Abdullah, NAN Kosai, NR Taher, M Rajan, R Chong, HY Agius, M Borg, E Bezzina, M Bugeja, R Vella-Baldacchino, M Spina, A Psaila, J Francois-Coridon, H Tolg, C Colombani, J-F Diaz-Zorrilla, C Ramos-De La Medina, A Corro-Diaz Gonzalez, S Jacobe, M Mapasse, D Snyder, E Oumer, R Osman, M Mohammad, A Anyanwu, L-J Sheshe, A Adesina, A Faturoti, O Taiwo, O Ibrahim, MH Nasir, AA Suleiman, SI Adeniyi, A Adesanya, O Adebanjo, A Osuoji, R Atobatele, K Ogunyemi, A Williams, O Oludara, M Oshodi, O Ademuyiwa, A Lawal, AO Alakaloko, F Elebute, O Osinowo, A Bode, C Adesuyi, A Tade, A Adekoya, A Nwokoro, C Ayandipo, OO Lawal, TA Ajao, AE Ali, SS Odeyemi, B Olori, S Popoola, A Adeyeye, A Adeniran, J Lossius, WJ Havemann, I Thorsen, K Narvestad, JK Soreide, K Wold, TB Nymo, L Elsiddig, M Dar, M Bhopal, KF Iftikhar, Z Furqan, MM Nighat, B Jawaid, M Khalique, A Zil-E-Ali, A Rashid, A Dharamshi, HA Naqvi, T Faraz, A Anwar, AW Yaseen, TM Shamsi, GS Shamsi, G Yaseen, T Anwer, W Paredes Decoud, H Aguilera, O Zelada Alvarez, II Marcelo Delgado, J Machain Vega, GM Segovia Lohse, HA Messa Aguilar, WL Cabala Chiong, JA Manchego Bautista, AC Huaman, E Zegarra, S Camacho, R Vergara Celis, JM Romani Pozo, DA Hamasaki, J Temoche, E Herrera-Matta, J Garcia Torres, CP Alvarez Barreda, LM Barrionuevo Ojeda, RR Garaycochea, O Castro Mollo, M Linares Delgado, MSDFT Fujii, F Aranzabal Durand, SY Arroyo Basto, CA Urbina Rojas, NM Shu Yip, SB Contreras Vergara, AL Rosas Moran, AE Borda Luque, G Rodriguez Castro, M Alvarado Jaramillo, R Manrique Sila, G Elizabeth Lopez, C Zapata Ponze De Leon, M Machaca, M Coasaca Huaraya, R Arenas, A Lopez, C Herrera Puma, CM Pino, W Hinojosa, C Zapata Ponze De Leon, M Limache, S Manrrique Sila, G Mercado Rodriguez, L-A Melo, R Costa-Maia, J Muralha, N Sauvat, F Dan, I Hogea, M Eduard, P Bratu, R-M Beuran, M Diaconescu, I-B Martian, B-V Iordache, F-M Vartic, M Vida, LC Muntean, LI Mironescu, AS Nsengimana, VJP Niragire, A Ingabire, JDLCA Niyirera, E Zanini, N Jovine, E Landolfo, G Alomar, IN Alnuqaydan, SA Altwigry, AM Othman, M Osman, N Alqahtani, E Alzahrani, M Alyami, R Aljohani, E Alhabli, I Mikwar, Z Almuallem, S Nawawi, A Bakhaidar, M Maghrabi, AA Alsaggaf, M Aljiffry, M Altaf, A Khoja, A Habeebullah, A Akeel, N Ghandora, N Almoflihi, A Huwait, A Al-shammari, A Al-Mousa, M Alghamdi, M Adham, W Albeladi, B Alfarsi, MA Mahdi, A Al Awwad, S Nouh, T Hassanain, M Aldhafeeri, S Sadig, N Algohary, O Aledrisy, M Gudal, A Alrifaie, A AlRowais, M Althwainy, A Shabkah, A Alamoudi, U Alrajraji, M Alghamdi, B Aljohani, S Daqeeq, A Al-Faifi, JJ Jennings, V Ngayu, N Moore, R Kong, V Kretzmann, H Connor, K Nel, D Sampson, C Panieri, E Sishuba, N Tun, M Mphatsoe, AM Carreira, J-A Teasdale, E Wagener, M Botes, S Du Plessis, D Fernandez-Bueno, F Aguilar-Jimenez, J Andres Garcia-Marin, J Solar Garcia, L Garcia Florez, LJ Arias Pacheco, RD Pagnozzi, J Jara Quezada, JH Luis Rodicio, J Minguez, G Rodriguez-Uria, R Ugalde, P Lopez-Arevalo, C Barneo, L Gonzales Stuva, JP Ortega-Vazquez, I Rodriguez, L Herrera, N Arachchi, PP Senanayake, WSMKJ Arachchige, LAJJ Sivaganesh, S Samaraweera, DI Thanusan, V Musa, AEK Balila, RMH Mohamed, MAEH Ali, H Elabdin, HZ Hassan, A Mahdi, S Ahmed, H Idris, SAI Elsayed, M Elsayed, M Mahmoud, M Boijsen, M Lundgren, P-O Gustafsson, U Kiasat, A Wogensen, F Jurdell, E Thorell, A Thorarinsdottir, H Utter, M Sundstrom, SM Wredberg, C Kjellin, A Nyberg, J Frisk, B Sund, M Andersson, L Gunnarsson, U Cengiz, Y Ahlqvist, S Bjorklund, I Royson, H Weber, P Pahlsson, H-I Borin, E Hjertberg, M Schmid, R Schivo, D Despotidis, V Breitenstein, S Staerkle, RF Schadde, E Deichsel, F Gerosa, A Nocito, A Raptis, DA Mijuskovic, B Zuber, M Eisner, L Kruspi, S Reinisch, KB Schoewe, C Novak, A Palma, AF Teufelberger, G Kimaro, M King, R Balkan, AZA Gumar, M Yavuz, MA Karabacak, U Lap, G Ozkan, BB Karakahya, M Adams, R Morton, R Henderson, L Gratton, R Clement, KD Chang, KY-C Mcnish, D Mcintosh, R Milligan, W Skelly, B Anderson-Knight, H Lawther, R Onimowo, J Shatkar, V Tharmalingam, S Woin, E Fautz, T Ziff, O Dindyal, S Arman, S Talukder, S Gadhvi, V Chew, LS Heath, J Blencowe, N Hallam, S Gash, K Mannu, GS Zachariades, D-C Snaith, AC Hettiarachchi, TS Nesaratnam, A Wheeler, J McCullagh, D Clements, JM Khan, A Koumpa, F Neophytou, C Roth, J Soon, WC Deputy, M Ahmed, A Ashton, A Vincent, J Almy, J Khan, T Allen, JLY Mcintyre, CJ Marshall, DC Sykes, M Behar, N Jordan, H Rajjoub, Y Sherman, T White, T Watts, A Ardley, R Arulampalam, T Shah, A Brown, D Blower, E Sutton, P Gasteratos, K Vimalachandran, D Magee, C Mcguigan, A Mcaleer, S Morgan, C Braungart, S Lafferty, K Labib, P Tanase, A Mangan, C Reza, L Woodward, H Gouldthorpe, C Turner, M Wild, JRL Malik, TAM Proctor, VK Hewage, K Davies, J Dubois, A Sarwary, S Zardab, A Grant, A Mcintyre, R Mogan, YP Ho, W Chong, BFHK Tewari, S Humm, G Farinella, E Hall, NJ Wright, NJ Major, CP Xerri, T Amin, J Farhad, M Camilleri-Brennan, JF Robertson, AGN Swann, J Richards, J Jabbar, A De Bono, P Attard, M Burns, H Macdonald, E Baldacchino, M Skehan, J Hall, TF Gimzewska, M Mclachlan, G Shah, J Giles, J Chiu, S Weber, B Chiu, SMY Highcock, S Hassan, M Beasley, W Vlachogiorgos, A Dias, S Maharaj, G Mcdonald, R Macdonald, A Witherspoon, P Baird, A Sarmah, P Green, N Youssef, H Cross, K Rees, CM Van Duren, B Upchurch, E Khan, K Abudeeb, H Hammad, A Karandikar, S Bowley, D Karim, A Chachulski, W Richardson, L Dawnay, G Thompson, B Mistry, A Ghetia, M Roy, S Al-Obaedi, O Das, K Prabhudesai, A Cocker, DM Tan, JJ Tyler, R Di Franco, F Ayyar, S Vivekanantham, S Gokani, S Gillespie, M Gudlaugsdottir, K Pezas, T Currow, C Kim, MY-H Birring, A Edwards, J Ali, A Das, S Jha, M Atkinson, K Luck, J Fozard, T Puttick, M Salama, Y Shah, R Ibrahem, AA Ebdewi, H Gravante, G El-Rabaa, S Nnajiuba, H Allott, R Bhargava, A Chan, Z Hassan, Z Makinde, M Hemingway, D Dean, R Boddy, A Aber, A Patel, V Parakh, J Parthiban, S Ubhi, HK Hosein, S-P Ward, S Malik, K Jennings, L Newton, T Alkhouri, M Kang, MK Houlden, C Barry, J Raza, I Farquharson, A Bhattacharya, S Chang, K Wilson, MSJ Neo, YN Ibrahim, I Chan, E Peck, FS Lim, PJ North, AS Blundell, R Williamson, A Fouad, D Minocha, A Mccarthy, K Court, E Chambers, A Yee, J Tham, JC Beaton, C Walsh, U Lockey, J Bokhari, S Howells, L Griffiths, M Yallop, L Singh, S Nasher, O Jackson, P Shariffuddin, AM Ho, WC Wilson, MSJ Pabla, G Ramzi, S Zeidan, S Doughty, J Sinha, S Davenport, R Lewis, J Duffy, L Mcaleer, E Williams, E Som, R Javed, O Boal, M Harrison, N Tafazal, H Brogden, T Griffiths, E Obute, RD Glover, TE Clark, DJ Boshnaq, M Akhtar, M Capleton, P Doughan, S Rabie, M Mohamed, I Samuel, D Dickson, L Kennedy, M Dempster, E Brown, E Maple, N Monaghan, E Wolf, B Garland, A Mcphee, A Anderson, D Anderson, R Hassan, S Smith, D Lund, J Boereboom, C Murphy, J Tierney, G Tou, S Zimmermann, EF Smart, NJ Warwick, AM Stasinou, T Daniels, I Findlay-Cooper, K Mitrasinovic, S Ray, S Varcada, M D'Souza, R Omara, S Spurr, M Parkinson, L Hanks, A Ma, J Abington, E Ramcharn, M Williams, G Winstanley, J Kennedy, ED Yeung, ENW Jones, C O'neill, S Lim, SJ Liew, I Nair, H Fairfield, C Oh, J Koh, S Wilson, A Fairfield, C Anandkumar, D Kirupagaran, A Jones, TF Torrance, HDT Fowler, AJ Chandrakumar, C Patel, P Ashraf, SF Lakhani, SM Mclean, AL Basson, S Batt, J Bowman, C Stoddart, M Benons, N Mason, C Harrison, R Quayle, J Barker, T Summerour, V Harper, E Smith, C Hampton, M Pitt, SK Ward, AE O'Connor, T Heywood, EG Chowdhury, A Hossaini, S Watson, NFS Mckechnie, D Farah, A Chun, A Koh, H Lim, G Sunderland, G Gould, L Munipalle, PC Rooney, H Browning, DRL Pereira, B Nemeth, K Decker, E Giuliani, S Shalaby, A Shaikh, S Tan, CY Palkhi, EYA Szczap, A Chidambaram, S Chen, CY Kulasabanathan, K Chhabra, S Kostov, E Harbord, P Barnacle, J Palliyil, MM Zikry, M Porter, J Raslan, C Hafiz, S Soltani, N Baillie, K Singh, P Sheth, S Patel, K Khalili, M Choi, J Benger, M Marples, L Macfarlane, A Thurairaja, R Boyce, T Whewell, H Jones, E Th'ng, F Robertson, N Mirza, A Saeed, H Galloway, S Elena, G Afzal, M Zakir, M Sodde, P Hand, C Sriram, A Clark, T Holton, P Livesey, A Sinha, Y Iqbal, FM Bharj, IS Rotundo, A Jenvey, C Slade, R Golding, D Haines, S Abdullah, AAN Tilston, TW Loughran, D Donoghue, D Giacci, L Sherif, MA Harrison, P Tang, A Kotecha, D Elshaer, M Urbonas, T Riaz, A Chapman, A Acharya, P Shalhoub, J Grossart, C McMorran, D Mlotshwa, M Hawkins, W Loizides, S Krishna, K Orchard, M Ho, CW Thomson, P Khan, S Taylor, F Shukla, J Howie, EE Macdonald, L Komolafe, O Mcintyre, N Cragg, J Parker, J Stewart, D Lintin, L Tracy, J Farooq, T Molina, G Kaafarani, H Beyene, R Sava, J Scott, M Swaroop, M Kennedy, R Azodo, IA Heffernan, D Chun, T Stephen, A Sion, M Weinstein, MS Punja, V Bugaev, N Goodstein, M Razmdjou, S Etchill, E Puyana, JC Kesinger, M Napolitano, L To, K Hemmila, M Todd, O Jenner, E Hoogakker, E Chen, JHC Ismail, L Roi, D Escobar, EG |
| Item Type: | Journal Article |
| Abstract: | Background Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. Methods This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. Results 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33–4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76–2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42–0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14–0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11–0.44) and SSI (OR 0.21 95% CI 0.09–0.45). Conclusion A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. |
| Issue Date: | 1-Aug-2018 |
| Date of Acceptance: | 12-Jan-2018 |
| URI: | http://hdl.handle.net/10044/1/64252 |
| DOI: | https://dx.doi.org/10.1007/s00464-018-6064-9 |
| ISSN: | 0930-2794 |
| Publisher: | Springer Verlag |
| Start Page: | 3450 |
| End Page: | 3466 |
| Journal / Book Title: | Surgical Endoscopy |
| Volume: | 32 |
| Issue: | 8 |
| Copyright Statement: | © The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Keywords: | Science & Technology Life Sciences & Biomedicine Surgery Appendicitis Appendectomy Global surgery Laparoscopic Operative standards Postoperative care Postoperative complications Surgical site infection SURGICAL CARE SURGERY APPENDECTOMY DISEASE BURDEN HEALTH GlobalSurg Collaborative 1103 Clinical Sciences |
| Publication Status: | Published |
| Online Publication Date: | 2018-04-05 |
| Appears in Collections: | Department of Surgery and Cancer |