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Development and validation of a symptom-based severity score for haemorrhoidal disease: the Sodergren score

Title: Development and validation of a symptom-based severity score for haemorrhoidal disease: the Sodergren score
Authors: Pucher, PH
Qurashi, M
Howell, A-M
Faiz, O
Ziprin, P
Darzi, A
Sodergren, MH
Item Type: Journal Article
Abstract: Aim One major obstacle in assessing the efficacy of treatment of haemorrhoids and the comparison of trials has been the lack of a standardized, validated symptom severity score. This study aimed to develop an objective, validated symptom‐based score of severity for haemorrhoids that can be used to compare treatments, monitor disease and assist in surgical decisions. Method A symptom and quality‐of‐life questionnaire was developed from the literature in conjunction with expert surgical opinion. The questionnaire was circulated to patients with confirmed haemorrhoids. A statistical model was used to derive a weighted score of symptoms most affecting patients' quality of life. Patients who were offered operative treatment were independently judged by specialists to have more severe symptoms, with further validation of the scoring system against treatment. Results Forty‐five patients were included in final validation analysis, of whom 44 (98%) reported multiple symptoms, the most common being rectal bleeding. Patient‐reported effects on quality of life were 47.5 ± 36.3 (1–100 visual analogue scale). Calculated symptom severity scores were used to compare patients receiving operative or ambulatory care, with significant difference in the scores (7.7 ± 3.9 vs 2.8 ± 3.5, P = 0.002) and a receiver operating characteristic area under the curve of 0.842. Conclusion A novel validated score for the assessment of haemorrhoidal disease adopting a standardized global score for symptom severity may have important implications in future for research, assessment and the management of this common pathology.
Issue Date: 1-Jul-2015
Date of Acceptance: 16-Oct-2014
URI: http://hdl.handle.net/10044/1/60893
DOI: https://dx.doi.org/10.1111/codi.12903
ISSN: 1462-8910
Publisher: WILEY-BLACKWELL
Start Page: 612
End Page: 618
Journal / Book Title: COLORECTAL DISEASE
Volume: 17
Issue: 7
Copyright Statement: © 2015 The Association of Coloproctology of Great Britain and Ireland. This is the accepted version of the following article: Pucher, P. H., Qurashi, M. , Howell, A. , Faiz, O. , Ziprin, P. , Darzi, A. and Sodergren, M. H. (2015), Development and validation of a symptom‐based severity score for haemorrhoidal disease: the Sodergren score. Colorectal Dis, 17: 612-618. doi:10.1111/codi.12903, which has been published in final form at https://dx.doi.org/10.1111/codi.12903
Sponsor/Funder: National Institute for Health Research
Funder's Grant Number: NF-SI-0510-10186
Keywords: Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
Surgery
Haemorrhoid
symptom score
severity score
QUALITY-OF-LIFE
RANDOMIZED-TRIAL
ARTERY LIGATION
DEARTERIALIZATION
MUCOPEXY
ANOPEXY
SF-6D
VAS
Adult
Aged
Aged, 80 and over
Area Under Curve
Female
Hemorrhoids
Humans
Male
Middle Aged
Quality of Life
ROC Curve
Severity of Illness Index
Surveys and Questionnaires
Symptom Assessment
Young Adult
1103 Clinical Sciences
Publication Status: Published
Online Publication Date: 2015-06-22
Appears in Collections:Department of Surgery and Cancer
Institute of Global Health Innovation