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Ultrasound Super-Resolution with Microbubble Contrast Agents

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Title: Ultrasound Super-Resolution with Microbubble Contrast Agents
Authors: Harput, S
Christensen-Jeffries, K
Brown, J
Eckersley, RJ
Dunsby, C
Tang, M-X
Item Type: Conference Paper
Abstract: Ultrasound super-resolution imaging can be achieved by localizing spatially isolated microbubble contrast agents over multiple imaging frames. In vivo images with resolutions of ~10-20 microns in deep tissue have been demonstrated. The technique has the potential to revolutionize the way micro-circulation can be visualized and quantified, and has implications in a wide range of clinical applications including cancer, diabetes and beyond. In this paper we describe the principle of the technique with in vivo results demonstrating the superior resolution achieved compared with existing ultrasound imaging. We also discuss the challenges and opportunities in the area of 3D imaging including, imaging speed, tissue motion and microbubble localization errors.
Issue Date: 25-Dec-2017
Date of Acceptance: 29-Oct-2017
URI: http://hdl.handle.net/10044/1/59728
DOI: https://dx.doi.org/10.1109/ICSENS.2017.8234244
ISSN: 1930-0395
Publisher: IEEE
Start Page: 1104
End Page: 1106
Journal / Book Title: 2017 IEEE SENSORS
Copyright Statement: ©2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor/Funder: Engineering & Physical Science Research Council (EPSRC)
Funder's Grant Number: EP/N015487/1
Conference Name: 16th IEEE SENSORS CONFERENCE
Keywords: Science & Technology
Technology
Engineering, Electrical & Electronic
Remote Sensing
Engineering
ultrasound super-resolution
super-localisation microscopy
microbubbles
contrast agents
DOPPLER
Publication Status: Published
Start Date: 2017-10-29
Finish Date: 2017-11-01
Conference Place: Glasgow, SCOTLAND
Online Publication Date: 2017-12-25
Appears in Collections:Physics
Bioengineering
Photonics
Faculty of Natural Sciences