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Hypothyroidism in the "Arnolfini Portrait" (1434) by Jan Van Eyck (1390-1441)

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Title: Hypothyroidism in the "Arnolfini Portrait" (1434) by Jan Van Eyck (1390-1441)
Authors: Ashrafian, H
Item Type: Journal Article
Abstract: Background The Arnolfni portrait painted by Jan van Eyck in 1434 remains one of the most puzzling yet alluring paintings of prerenaissance western art. Purpose The painting is renowned for its exactitude in brush strokes, textures and the distinctive morphology of the main character Arnolfni. The nature of these requires pathological consideration. Methods Diagnostic and pathological analysis of the painting. Results A number of pathological abnormalities are noted in the face of the main character including loss of outer third of the eyebrow (Sign of Hertoghe), bilateral ptosis and melasma of the forehead. These together support a diagnosis of hypothyroidism. Conclusions This novel diagnosis ofers an additional perspective to this enigmatic portrait, and can add to the comprehension of the method, origin and pathological associations of this prominent painting from a genius artist.
Issue Date: 9-Sep-2017
Date of Acceptance: 17-Aug-2017
URI: http://hdl.handle.net/10044/1/56197
DOI: https://dx.doi.org/10.1007/s40618-017-0751-6
ISSN: 0391-4097
Publisher: Springer Verlag
Start Page: 145
End Page: 147
Journal / Book Title: Journal of Endocrinological Investigation
Volume: 41
Issue: 1
Copyright Statement: © The Author(s) 2017. This article is an open access publication
Keywords: Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
1103 Clinical Sciences
Publication Status: Published
Appears in Collections:Department of Surgery and Cancer