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Metabolic phenotyping of diet and dietary Intake

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Title: Metabolic phenotyping of diet and dietary Intake
Authors: Brignardello, J
Holmes, E
Garcia-Perez, I
Item Type: Chapter
Abstract: Nutrition provides the building blocks for growth, repair, and maintenance of the body and is key to maintaining health. Exposure to fast foods, mass production of dietary components, and wider importation of goods have challenged the balance between diet and health in recent decades, and both scientists and clinicians struggle to characterize the relationship between this changing dietary landscape and human metabolism with its consequent impact on health. Metabolic phenotyping of foods, using high-density data-generating technologies to profile the biochemical composition of foods, meals, and human samples (pre- and postfood intake), can be used to map the complex interaction between the diet and human metabolism and also to assess food quality and safety. Here, we outline some of the techniques currently used for metabolic phenotyping and describe key applications in the food sciences, ending with a broad outlook at some of the newer technologies in the field with a view to exploring their potential to address some of the critical challenges in nutritional science.
Issue Date: 23-Jan-2017
URI: http://hdl.handle.net/10044/1/53481
DOI: https://dx.doi.org/10.1016/bs.afnr.2016.12.002
ISBN: 978-0-12-811916-7
Start Page: 231
End Page: 270
Journal / Book Title: Advances in Food and Nutrition Research
Volume: 81
Copyright Statement: © 2017 Elsevier Inc. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Gut microbiome
Mass spectrometry
Metabolic profiling
Multivariate modeling
NMR spectroscopy
Personalized nutrition
Energy Metabolism
Food Analysis
Nutritional Physiological Phenomena
Nutrition & Dietetics
Publication Status: Published
Article Number: 7
Appears in Collections:Department of Surgery and Cancer