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Using biomaterials to rewire the process of wound repair
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Title: | Using biomaterials to rewire the process of wound repair |
Authors: | Stejskalova, A Almquist, BD |
Item Type: | Journal Article |
Abstract: | Wound healing is one of the most complex processes that our bodies must perform. While our ability to repair wounds is often taken for granted, conditions such as diabetes, obesity, or simply old age can significantly impair this process. With the incidence of all three predicted to continue growing into the foreseeable future, there is an increasing push to develop strategies that facilitate healing. Biomaterials are an attractive approach for modulating all aspects of repair, and have the potential to steer the healing process towards regeneration. In this review, we will cover recent advances developing biomaterials that actively modulate the process of wound healing, and will provide insight into how biomaterials can be used to simultaneously rewire multiple phases of the repair process. |
Issue Date: | 22-Jun-2017 |
Date of Acceptance: | 22-Jun-2017 |
URI: | http://hdl.handle.net/10044/1/49674 |
DOI: | https://dx.doi.org/10.1039/c7bm00295e |
ISSN: | 2047-4849 |
Publisher: | Royal Society of Chemistry |
Start Page: | 1421 |
End Page: | 1434 |
Journal / Book Title: | Biomaterials Science |
Volume: | 5 |
Copyright Statement: | © The Royal Society of Chemistry 2017. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (https://creativecommons.org/licenses/by/3.0/) |
Sponsor/Funder: | Wellcome Trust Wellcome Trust Rosetrees Trust Rosetrees Trust Diabetes Research & Wellness Foundation |
Funder's Grant Number: | 109838/Z/15/Z 109838/Z/15/Z A1071 A1071 1770 |
Keywords: | Science & Technology Technology Materials Science, Biomaterials Materials Science MESENCHYMAL STEM-CELLS RECEPTOR TYROSINE KINASES GROWTH-FACTOR RECEPTOR PLATELET LYSATE IN-VITRO INFLAMMATORY RESPONSE EXTRACELLULAR-MATRIX TISSUE REGENERATION DIABETIC WOUNDS LIPID MEDIATORS |
Publication Status: | Published |
Appears in Collections: | Bioengineering Faculty of Engineering |