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Using biomaterials to rewire the process of wound repair

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Title: Using biomaterials to rewire the process of wound repair
Authors: Stejskalova, A
Almquist, BD
Item Type: Journal Article
Abstract: Wound healing is one of the most complex processes that our bodies must perform. While our ability to repair wounds is often taken for granted, conditions such as diabetes, obesity, or simply old age can significantly impair this process. With the incidence of all three predicted to continue growing into the foreseeable future, there is an increasing push to develop strategies that facilitate healing. Biomaterials are an attractive approach for modulating all aspects of repair, and have the potential to steer the healing process towards regeneration. In this review, we will cover recent advances developing biomaterials that actively modulate the process of wound healing, and will provide insight into how biomaterials can be used to simultaneously rewire multiple phases of the repair process.
Issue Date: 22-Jun-2017
Date of Acceptance: 22-Jun-2017
URI: http://hdl.handle.net/10044/1/49674
DOI: https://dx.doi.org/10.1039/c7bm00295e
ISSN: 2047-4849
Publisher: Royal Society of Chemistry
Start Page: 1421
End Page: 1434
Journal / Book Title: Biomaterials Science
Volume: 5
Copyright Statement: © The Royal Society of Chemistry 2017. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (https://creativecommons.org/licenses/by/3.0/)
Sponsor/Funder: Wellcome Trust
Wellcome Trust
Rosetrees Trust
Rosetrees Trust
Diabetes Research & Wellness Foundation
Funder's Grant Number: 109838/Z/15/Z
109838/Z/15/Z
A1071
A1071
1770
Keywords: Science & Technology
Technology
Materials Science, Biomaterials
Materials Science
MESENCHYMAL STEM-CELLS
RECEPTOR TYROSINE KINASES
GROWTH-FACTOR RECEPTOR
PLATELET LYSATE
IN-VITRO
INFLAMMATORY RESPONSE
EXTRACELLULAR-MATRIX
TISSUE REGENERATION
DIABETIC WOUNDS
LIPID MEDIATORS
Publication Status: Published
Appears in Collections:Bioengineering
Faculty of Engineering